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Ac9-25 acetate is an annexin AI peptide and activates the neutrophil reduced nicotinamide adenine dinucleotide phosphate oxidase through FPR but not through FPRL1.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $111 | In Stock | |
5 mg | $250 | In Stock | |
10 mg | $371 | In Stock | |
25 mg | $593 | In Stock | |
50 mg | $798 | In Stock | |
100 mg | $1,070 | In Stock | |
200 mg | $1,430 | In Stock |
Description | Ac9-25 acetate is an annexin AI peptide and activates the neutrophil reduced nicotinamide adenine dinucleotide phosphate oxidase through FPR but not through FPRL1. |
In vitro | At a concentration of 20 μM, the N-terminal annexin I peptides Ac9-25 acetate markedly interfere with the transendothelial passage of neutrophils. Peptides derived from the N-terminal domains of other annexins do not elicit an inhibitory effect. Titration experiments show that a 50% inhibition of neutrophil transmigration is observed at ~5 μM annexin I peptide with Ac9-25 acetate[1]. |
Alias | Ac9-25 acetate(284040-76-2 free base) |
Molecular Weight | 2243.38 |
Formula | C101H147N23O35 |
Smiles | CC(O)=O.O=C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C |
Relative Density. | no data available |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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