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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Allo-aca TFA, a potent and specific leptin receptor antagonist peptide, inhibits leptin signaling and function across various in vitro and in vivo models [1] [2]. |
In vitro | Allo-aca TFA impedes the leptin-stimulated growth of MDA-MB-231 cells at a 50 pM concentration. |
In vivo | In an MDA-MB-231 orthotopic mouse xenograft model, subcutaneous administration of Allo-aca TFA markedly increased the mean survival time from 15.4 days in untreated controls to 24 days and 28.1 days at dosages of 0.1 mg/kg/day and 1 mg/kg/day, respectively [1]. |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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