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Delta (Phospho) Sleep Inducing Peptide

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Delta (Phospho) Sleep Inducing Peptide

Catalog No. T82587Cas No. 70754-23-3

Delta (Phospho) Sleep Inducing Peptide (DSIP-P), a peptide that promotes sustained sleep, induces changes in circadian locomotor activity in rats [1][2][3].

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Product Introduction

Bioactivity

Description	Delta (Phospho) Sleep Inducing Peptide (DSIP-P), a peptide that promotes sustained sleep, induces changes in circadian locomotor activity in rats [1][2][3].
In vitro	Delta (Phospho) Sleep Inducing Peptide, at concentrations ranging from 20 to 300 nM, enhances the activity of rat pineal N-acetyltransferase (NAT), which is stimulated by norepinephrine in vitro [3].
In vivo	Delta (Phospho) Sleep Inducing Peptide (0.1 nmol/kg; i.v.; once daily for 4 times) alters circadian locomotor activity [1]. Administered into the third cerebroventricle of male rats at 20 or 200 pmol/kg immediately before the dark period, it enhances slow-wave and paradoxical sleep during the dark period, with 200 pmol/kg doing so without reducing sleep latency [2].
Alias	DSIP-P

Chemical Properties

Molecular Weight	928.79
Formula	C35H49N10O18P
Cas No.	70754-23-3

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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