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Argipressin

Argipressin
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Argipressin

Catalog No. T7434Cas No. 113-79-1
Argipressin (Vasopressin) is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.
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Pack SizePriceAvailabilityQuantity
1 mg$467-10 days
2 mg$587-10 days
5 mg$917-10 days
10 mg$1207-10 days
25 mg$1597-10 days
50 mg$1897-10 days
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Product Introduction

Bioactivity
Description
Argipressin (Vasopressin) is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.
In vitro
Argipressin stimulates the intracellular release of calcium in A7r5 cells (EC50 = 5 nM)[1].
In vivo
In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.
AliasArg8-vasopressin, Vasopressin, AVP
Chemical Properties
Molecular Weight1084.23
FormulaC46H65N15O12S2
Cas No.113-79-1
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 100 mg/mL (92.23 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.9223 mL4.6116 mL9.2231 mL46.1157 mL
5 mM0.1845 mL0.9223 mL1.8446 mL9.2231 mL
10 mM0.0922 mL0.4612 mL0.9223 mL4.6116 mL
20 mM0.0461 mL0.2306 mL0.4612 mL2.3058 mL
50 mM0.0184 mL0.0922 mL0.1845 mL0.9223 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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