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Vasopressin
Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pituitary-adrenal axis, increasing the amount of solute free water reabsorbed from the renal tubule's colate back into the circulation, narrowing arteries to increase pressure, enhancing the stimulating effect of corticotropin releasing factor to regulate pituitary corticotropin secretion. Vasopressin acts as a neurotransmitter during nerve conduction by binding to specific G-protein-coupled receptors.
Catalog No. T9857Cas No. 11000-17-2
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Vasopressin
Catalog No. T9857Cas No. 11000-17-2
Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pituitary-adrenal axis, increasing the amount of solute free water reabsorbed from the renal tubule's colate back into the circulation, narrowing arteries to increase pressure, enhancing the stimulating effect of corticotropin releasing factor to regulate pituitary corticotropin secretion. Vasopressin acts as a neurotransmitter during nerve conduction by binding to specific G-protein-coupled receptors.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $39 | In Stock | |
| 10 mg | $64 | In Stock | |
| 25 mg | $97 | In Stock | |
| 50 mg | $163 | In Stock | |
| 100 mg | $243 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $78 | In Stock |
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CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Vasopressin (argipressin), a cyclic nine-peptide synthesized by hypothalamic neurons, is one of the hormones involved in peptide prohormone synthesis. Vasopressin is involved in the regulation process of hypothalamic-pituitary-adrenal axis, increasing the amount of solute free water reabsorbed from the renal tubule's colate back into the circulation, narrowing arteries to increase pressure, enhancing the stimulating effect of corticotropin releasing factor to regulate pituitary corticotropin secretion. Vasopressin acts as a neurotransmitter during nerve conduction by binding to specific G-protein-coupled receptors. |
| In vitro | AVP (0.01 nM-1 μM) induces Ca2+ elevation in Chinese hamster ovary cells expressing rat or human V1b receptors.[1] |
| In vivo | Vasopressin (0.03-0.3 μg/kg; i.p.) enhances corticotropin release elicited by exogenous corticoliberin and amplifies corticotropin secretion following dehydration.[1] Vasopressin (0.001-0.1 mg/kg; i.p.) significantly promotes proximity, wherein rats encountering each other for the first time exhibit passive side-by-side positioning.[2] |
| Alias | antidiuretic hormone (ADH), argipressin, arginine vasopressin (AVP) |
| Molecular Weight | 1084.24 |
| Formula | C46H65N15O12S2 |
| Cas No. | 11000-17-2 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90.0 mg/mL (83.0 mM), Sonication is recommended. H2O: 45.0 mg/mL (41.5 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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