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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | Poneratoxin, a peptide toxin, regulates sodium currents in mammals and induces long-lasting pain [1]. |
In vivo | Poneratoxin induces both immediate and sustained nocifensive behaviors in the C57BL/6 J mouse model when administered via a single intraplantar injection at doses ranging from 20 to 600 pmol. In the blowfly model, a single intraperitoneal injection at doses between 0 and 100 nmol/g results in paralysis, with a PD 50 (1 h) of 74.3 nmol/g [1]. [Animal Model: C57BL/6 J mice model [1] Dosage: 20 to 600 pmol Administration: intraplantar injection, single dose Result: Caused spontaneous nocifensive behaviours. Animal Model: blowflies model [1] Dosage: 0-100 nmol/g Administration: Ip, single dose Result: Caused paralysis.] |
Molecular Weight | 2756.35 |
Formula | C129H215N33O31S |
Cas No. | 137084-94-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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