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Atrial natriuretic factor (1-28) (human, porcine)

Name: Atrial natriuretic factor (1-28) (human, porcine)
Brand: TargetMol
SKU: T41065
Rating: 4.5 (1 reviews)

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Catalog No. T41065Cas No. 91917-63-4

Alias Atrial natriuretic peptide (1-28), Atrial natriuretic factor (1-28) (human, porcine)

Atrial natriuretic factor (1-28) from both human and porcine sources is a potent suppressor of pro-opiomelanocortin (POMC) mRNA, exerting only a modest inhibitory effect on βEP-LI release.

Atrial natriuretic factor (1-28) (human, porcine)

😃Good

Catalog No. T41065Alias Atrial natriuretic peptide (1-28), Atrial natriuretic factor (1-28) (human, porcine)Cas No. 91917-63-4

Atrial natriuretic factor (1-28) from both human and porcine sources is a potent suppressor of pro-opiomelanocortin (POMC) mRNA, exerting only a modest inhibitory effect on βEP-LI release.

Pack Size	Price	Availability	Quantity
1 mg	$1,130	35 days

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Product Introduction

Bioactivity

Description	Atrial natriuretic factor (1-28) from both human and porcine sources is a potent suppressor of pro-opiomelanocortin (POMC) mRNA, exerting only a modest inhibitory effect on βEP-LI release.
In vitro	ANF-(1-28) significantly enhances the levels of guanosine 3',5'-cyclic monophosphate (cGMP) from 1.3 +/- 0.3 to 106 +/- 22 pmol cGMP/10^6 cells, with a 50% effective dosage (ED 50) of 1.2 nM[1].
In vivo	The infusion of ANF-(1-28) at a dosage of 0.5 μg/kg/min significantly reduces the increase in plasma creatinine levels by about 50% daily throughout the study period[3].
Alias	Atrial natriuretic peptide (1-28), Atrial natriuretic factor (1-28) (human, porcine)

Chemical Properties

Molecular Weight	3082.49
Formula	C₁₂₇H₂₀₅N₄₅O₃₉S₃
Cas No.	91917-63-4

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

Atrial natriuretic peptideAtrial natriuretic factor (1 28) (human, porcine)Atrial natriuretic factor (128) (human, porcine)Atrial natriuretic factor

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