Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Description | GLP-1(32-36)amide is a pentapeptide compound derived from the C terminus of the glucoregulatory hormone GLP-1. This compound has shown potential in inhibiting weight gain and regulating glucose metabolism in diabetic mice[1][2]. |
In vitro | GLP-1(32-36)amide (0.1-10 μM; 24 h) maintains cell viability and reduces apoptosis in INS‐1 cells treated with Streptozotocin (STZ; 1 μM) [2]. |
In vivo | GLP-1(32-36)amide (1 μmol/kg; i.p. once daily for 21 days) protects islets from damage, inhibits weight gain, and alleviates polydipsia symptoms in diabetic mice[2]. A single dose of GLP-1(32-36)amide (1 μmol/kg; i.p.) slightly reduces mean glucose levels 30 minutes post-glucose challenge in normal mice[2]. GLP-1(32-36)amide (50-70 nmol/kg/d; infusion for 12-16 weeks) prevents diet-induced obesity and hepatic steatosis in high-fat-fed mice[3]. Animal Model: Male KM mice (6-8 weeks; 18-22 g) injected with STZ[2]. |
Molecular Weight | 570.74 |
Formula | C25H50N10O5 |
Cas No. | 1417302-71-6 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 250 mg/mL (438.04 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.