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Dimethyl DL-Glutamate (hydrochloride)

Dimethyl DL-Glutamate (hydrochloride)
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Purity:98%
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Dimethyl DL-Glutamate (hydrochloride)

Catalog No. T7658Cas No. 13515-99-6
Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes.
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Pack SizePriceAvailabilityQuantity
1 g$29In Stock
1 mL x 10 mM (in DMSO)$45In Stock
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Product Introduction

Bioactivity
Description
Dimethyl DL-glutamate is a cell-permeant glutamic acid derivative that enhances insulin release in response to glucose in isolated islets and in animal models of diabetes.
In vitro
Dimethyl DL-Glutamate (hydrochloride) ?potentiates the insulinotropic potential of glyburide and glucagon-like peptide 1[1]. Dimethyl DL-glutamate is used as a cell-permeable form of glutamate in studies of glutamate action in β-cells[2].
Chemical Properties
Molecular Weight211.64
FormulaC7H14ClNO4
Cas No.13515-99-6
Storage & Solubility Information
Storagekeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 27.5 mg/mL (129.94 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.7250 mL23.6250 mL47.2500 mL236.2502 mL
5 mM0.9450 mL4.7250 mL9.4500 mL47.2500 mL
10 mM0.4725 mL2.3625 mL4.7250 mL23.6250 mL
20 mM0.2363 mL1.1813 mL2.3625 mL11.8125 mL
50 mM0.0945 mL0.4725 mL0.9450 mL4.7250 mL
100 mM0.0473 mL0.2363 mL0.4725 mL2.3625 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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