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1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

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Catalog No. T83826Cas No. 57653-85-7
Alias PCDD 67, 1,2,3,6,7,8-HxCDD

1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.

1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

😃Good
Catalog No. T83826Alias PCDD 67, 1,2,3,6,7,8-HxCDDCas No. 57653-85-7
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.
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60 μg$1,52035 days
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Product Introduction

Bioactivity
Description
1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin, a polychlorinated dibenzodioxin (PCDD), acts as an agonist for the aryl hydrocarbon receptor (AhR; EC50s = 5.4 and 9.3 nM at 4 and 8 h, respectively, in a reporter assay). It has been observed to reduce antibody production against sheep red blood cells in mice at doses of 0.5 and 2 µg/kg. This compound has been detected in animal feed and in the vicinity of municipal waste incinerators.
AliasPCDD 67, 1,2,3,6,7,8-HxCDD
Chemical Properties
Molecular Weight390.86
FormulaC12H2Cl6O2
Cas No.57653-85-7
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
nonane:toluene (8:2): soluble

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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