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TCL1(10-24) is an Akt inhibitor encompassing the betaA strand of human TCL1. It interacts with the Akt PH domain, preventing phosphoinositide binding and thereby inhibiting membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis, demonstrating its capacity to suppress tumor growth in vivo [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | TCL1(10-24) is an Akt inhibitor encompassing the betaA strand of human TCL1. It interacts with the Akt PH domain, preventing phosphoinositide binding and thereby inhibiting membrane translocation and activation of Akt. TCL1(10-24) inhibits cellular proliferation and anti-apoptosis, demonstrating its capacity to suppress tumor growth in vivo [1]. |
Molecular Weight | 1871.06 |
Formula | C88H123N23O23 |
Cas No. | 835655-37-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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