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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $215 | 7-10 days | |
5 mg | $847 | 7-10 days | |
10 mg | $1,410 | 7-10 days |
Description | Endothelin 1 (swine, human), a synthetic peptide mirroring the sequence of both human and swine Endothelin 1, functions as a robust endogenous vasoconstrictor by interacting with two receptor types, ETA and ETB. |
In vitro | Endothelin-1 (ET-1), a potent endogenous vasoconstrictor primarily secreted by endothelial cells, operates via ETA and ETB receptors. Beyond its vasoconstrictive effect, ET-1 contributes to vascular cell fibrosis and prompts the generation of reactive oxygen species. Additionally, ET-1 is implicated in proinflammatory mechanisms by elevating superoxide anion output and cytokine release. |
Molecular Weight | 2491.9 |
Formula | C109H159N25O32S5 |
Cas No. | 117399-94-7 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||
Solubility Information | H2O: 50 mg/mL (20.07 mM) | |||||||||||||||
Solution Preparation Table | ||||||||||||||||
H2O
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