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Acetyl Angiotensinogen (1-14), porcine Acetate

Acetyl Angiotensinogen (1-14), porcine Acetate
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Purity:95.71%
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Acetyl Angiotensinogen (1-14), porcine Acetate

Catalog No. T21582L
Acetyl Angiotensinogen (1-14), porcine Acetate is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH. The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor. 
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Pack SizePriceAvailabilityQuantity
5 mg$53In Stock
10 mg$74In Stock
25 mg$97In Stock
50 mg$157In Stock
100 mg$236In Stock
200 mg$353In Stock
1 mL x 10 mM (in DMSO)$116In Stock
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Product Introduction

Bioactivity
Description
Acetyl Angiotensinogen (1-14), porcine Acetate is a peptide with the sequence AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH. The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.
In vitro
The renin-angiotensin system?was extracted from blood with 70% acetone and had a short pressor effect.?The renin acted enzymatically on a plasma protein to produce the new substance.?
In vivo
The protein encoded by the Angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor.?Pre-angiotensinogen is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure.?The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.?Angiotensin II is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia[2].
AliasAcetyl Angiotensinogen (1-14), porcine Acetate(66641-26-7 Free base)
Chemical Properties
Molecular Weight1861.1
FormulaC89H129N21O23
Cas No.
Storage & Solubility Information
Storagekeep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 162mg/mL(89.95mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM0.5373 mL2.6866 mL5.3732 mL26.8658 mL
5 mM0.1075 mL0.5373 mL1.0746 mL5.3732 mL
10 mM0.0537 mL0.2687 mL0.5373 mL2.6866 mL
20 mM0.0269 mL0.1343 mL0.2687 mL1.3433 mL
50 mM0.0107 mL0.0537 mL0.1075 mL0.5373 mL

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