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Anti-Metabolism Disease Compound Library

Catalog No. L5200
  Library Compound List   Excel SDF

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1558 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 1558 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L5200)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

Autophagy (241)
Apoptosis (189)
P450 (157)
Endogenous Metabolite (128)
Dehydrogenase (85)
AMPK (81)
Antibacterial (80)
PDE (77)
PPAR (72)
PI3K (55)
Antibiotic (51)
COX (49)
Glucocorticoid Receptor (39)
MAO (37)
Reactive Oxygen Species (37)
HSP (35)
HIV Protease (34)
Ferroptosis (32)
mTOR (32)
Parasite (31)
Potassium Channel (31)
FAAH (28)
Carbonic Anhydrase (27)
Akt (27)
NF-κB (27)
Lipoxygenase (26)
Calcium Channel (25)
Proteasome (25)
Antifungal (24)
Phosphatase (24)
Mitophagy (24)
GSK-3 (24)
Retinoid Receptor (23)
Phospholipase (23)
Influenza Virus (22)
RAAS (22)
DNA/RNA Synthesis (22)
Casein Kinase (21)
HIF/HIF Prolyl-Hydroxylase (20)
Mitochondrial Metabolism (20)
Monoamine Oxidase (20)
FXR (19)
DPP-4 (18)
NADPH (17)
Glucosidase (17)
ROCK (17)
5-HT Receptor (16)
CDK (16)
Transferase (16)
AChR (15)
Adrenergic Receptor (15)
HMG-CoA Reductase (15)
SARS-CoV (14)
GPR (14)
AhR (13)
HCV Protease (13)
Indoleamine 2,3-Dioxygenase (IDO) (13)
Reductase (13)
Sodium Channel (12)
PKA (12)
Adenosine Receptor (12)
IL Receptor (12)
Virus Protease (12)
Prostaglandin Receptor (12)
ATM/ATR (12)
ERK (11)
HIF (11)
MMP (11)
PARP (11)
Fatty Acid Synthase (11)
GABA Receptor (11)
HBV (11)
Glucokinase (11)
DHFR (11)
TNF (11)
Lipase (11)
SGLT (11)
Histamine Receptor (11)
S6 Kinase (11)
DNA-PK (11)
Wnt/beta-catenin (10)
transporter (10)
PKC (10)
Tyrosinase (10)
ROR (10)
Aryl Hydrocarbon Receptor (9)
ROS (9)
Cannabinoid Receptor (9)
Hydroxylase (9)
Caspase (9)
Serine Protease (9)
Liver X Receptor (9)
Estrogen/progestogen Receptor (9)
Estrogen Receptor/ERR (9)
PDK (8)
Glutathione Peroxidase (8)
Xanthine Oxidase (8)
NO Synthase (8)
ATPase (8)
Reverse Transcriptase (8)
HSV (8)
Dopamine Receptor (8)
Isocitrate Dehydrogenase (IDH) (8)
IκB/IKK (8)
Thrombin (8)
Interleukin (8)
JNK (8)
STAT (8)
NAMPT (8)
Factor Xa (8)
AChE (8)
Antifolate (8)
Nrf2 (7)
Stearoyl-CoA Desaturase (SCD) (7)
HDAC (7)
Cysteine Protease (7)
UGT (7)
PAI-1 (7)
Glucagon Receptor (7)
Lipid (7)
Topoisomerase (7)
IDO (7)
PKM (7)
Acyltransferase (6)
TRP/TRPV Channel (6)
Opioid Receptor (6)
P-gp (6)
Phosphorylase (6)
Neprilysin (6)
Sirtuin (6)
VEGFR (6)
Aminopeptidase (6)
Src (6)
BCL (5)
iGluR (5)
Beta Amyloid (5)
Microtubule Associated (5)
MEK (5)
SGK (5)
Androgen Receptor (5)
p38 MAPK (5)
c-Met/HGFR (5)
Chloride channel (5)
CETP (5)
FLT (5)
Serine/threonin kinase (4)
JAK (4)
CCR (4)
GluR (4)
NOS (4)
Aurora Kinase (4)
CAT (4)
Anti-infection (4)
Norepinephrine (4)
DNA (4)
CaMK (4)
Leukotriene Receptor (4)
ribosome (4)
LDL (4)
TGF-beta/Smad (4)
ATP Citrate Lyase (4)
GPCR19 (4)
RSV (4)
IGF-1R (3)
Carboxypeptidase (3)
Acetyl-CoA Carboxylase (3)
OAT (3)
Decarboxylase (3)
Thyroid hormone receptor(THR) (3)
Adiponectin receptor (3)
Hexokinase (3)
SIK (3)
Annexin A (3)
TAM Receptor (3)
P2Y Receptor (3)
Antioxidant (3)
ABC (3)
Integrin (3)
Drug Metabolite (3)
Antifection (3)
FGFR (3)
BACE (3)
c-RET (3)
PERK (3)
NADPH-oxidase (3)
Ras (3)
NPC1L1 (3)
MRP (3)
Vasopressin Receptor (3)
Endothelin Receptor (3)
Histone Demethylase (2)
Sigma receptor (2)
Trk receptor (2)
ASK (2)
Amino Acids and Derivatives (2)
LTR (2)
ALK (2)
Histone Methyltransferase (2)
ROS Kinase (2)
CFTR (2)
GST (2)
MLK (2)
p53 (2)
Proton pump (2)
Progesterone Receptor (2)
Chk (2)
Antiviral (2)
Nucleoside Antimetabolite/Analog (2)
Gap Junction Protein (2)
PDGFR (2)
EGFR (2)
E1/E2/E3 Enzyme (2)
Hedgehog/Smoothened (2)
Syk (2)
PAK (2)
Glutaminase (2)
cell cycle arrest (2)
Adenosine deaminase (2)
c-Kit (2)
Epigenetic Reader Domain (2)
MAPK (2)
Rho (2)
PGC-1α (2)
Tyrosine Kinases (2)
OX Receptor (2)
Epoxide Hydrolase (2)
Neurokinin receptor (2)
HER (1)
BMI-1 (1)
Complement System (1)
c-Fms (1)
CRISPR/Cas9 (1)
Aromatase (1)
cholecystokinin (1)
LPA Receptor (1)
PI4K (1)
DNA Methyltransferase (1)
Platelet aggregation (1)
DNA Alkylation (1)
MELK (1)
IFNAR (1)
IAP (1)
Serotonin Transporter (1)
Pim (1)
VDAC (1)
N-Acetylglucosaminyltransferase (1)
CaSR (1)
Galectin (1)
Melatonin Receptor (1)
Tie-2 (1)
RAR/RXR  (1)
DYRK (1)
aconitase (1)
DNA Alkylator/Crosslinker (1)
Immunology/Inflammation related (1)
LPL Receptor (1)
Arginase (1)
YAP (1)
DprE1 (1)
stilbene oxidase (1)
Hydrogenase (1)
Monocarboxylate transporter (1)
Transaminase (1)
GSNOR (1)
Adenylyl cyclase (1)
Mdm2 (1)
advanced glycation end products (1)
CSF-1R (1)
FLAP (1)
Pyroptosis (1)
Bradykinin Receptor (1)
hCE (1)
GluCls (1)
Free radical scavengers (1)
LRRK2 (1)
TLR (1)
Glutathione reductase (1)
PGE Synthase (1)
Beta-Secretase (1)
BCRP (1)
Telomerase (1)
PAD (1)
CXCR (1)
Thioredoxin (1)
RIP kinase (1)
Bombesin Receptor (1)
MAGL (1)
PROTAC Linker (1)
Smo (1)
Guanylate cyclase (1)
Anion Exchanger (1)
Monoamine Transporter (1)
DNA gyrase (1)
NMDAR (1)
MT Receptor (1)
GRK (1)
FABP (1)
Bcr-Abl (1)
S1P Receptor (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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