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Anti-Metabolism Disease Compound Library

Catalog No. L5200
  Library Compound List   Excel SDF

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of the cells and the organism, including catabolism and anabolism, and is one way the body maintains homeostasis. The main focus in metabolism research area is the biological regulatory mechanism and its role in obesity, diabetes, cardiovascular diseases, and cancer. The unique collection of 1558 small chemicals targeting metabolism diseases will provide the support for metabolism research and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
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Product Description

  • A unique collection of 1558 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved for marketing by FDA, EMA, or NMPA;
  • Covers various major targets including CYP, FAAH, IDO, MAO, etc., in diabetes, obesity, hypertriglyceridemia, hypercholesterolemia, etc.; Effective tool for cell metabolism research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L5200)

Library Composition

Endogenous Metabolite (171)
Dehydrogenase (85)
P450 (84)
PDE (78)
PPAR (72)
Glucocorticoid Receptor (43)
COX (40)
MAO (39)
Vitamin (37)
HSP (35)
Glucokinase (29)
Carbonic Anhydrase (29)
AMPK (28)
Lipoxygenase (26)
Potassium Channel (24)
RAAS (23)
Phospholipase (23)
Autophagy (21)
Retinoid Receptor (21)
Casein Kinase (20)
FXR (18)
AChR (18)
DPP-4 (17)
NADPH (17)
NF-κB (17)
Transferase (16)
GPR (16)
Calcium Channel (15)
FAAH (14)
ROCK (14)
HIV Protease (14)
Phosphatase (14)
AhR (14)
HMG-CoA Reductase (14)
IDO (13)
Reductase (13)
Adrenergic Receptor (12)
Mitochondrial Metabolism (12)
DNA/RNA Synthesis (11)
DHFR (11)
SGLT (11)
HIF (11)
5-HT Receptor (11)
Fatty Acid Synthase (10)
Hydroxylase (10)
Estrogen/progestogen Receptor (10)
Lipase (10)
IL Receptor (10)
Liver X Receptor (10)
HIF/HIF Prolyl-Hydroxylase (10)
Apoptosis (10)
ROR (9)
ROS (9)
TNF (9)
Glucagon Receptor (9)
transporter (8)
Factor Xa (8)
MMP (8)
Serine Protease (8)
Wnt/beta-catenin (8)
Histamine Receptor (8)
Proteasome (8)
Sodium Channel (8)
PKA (8)
CDK (8)
UGT (7)
PKM (7)
Thrombin (7)
Lipid (7)
Tyrosinase (7)
ATPase (6)
PKC (6)
Phosphorylase (6)
Antibacterial (6)
Aminopeptidase (6)
Antifection (6)
Reverse Transcriptase (6)
HCV Protease (6)
NAMPT (6)
Caspase (6)
PAI-1 (6)
Sirtuin (6)
Cysteine Protease (6)
MPO (6)
Cannabinoid Receptor (6)
HBV (5)
GSK-3 (5)
Opioid Receptor (5)
mTOR (5)
p38 MAPK (5)
MRP (5)
HDAC (5)
Microtubule Associated (5)
JNK (5)
IκB/IKK (5)
ERK (5)
VEGFR (5)
Prostaglandin Receptor (5)
CETP (5)
Vasopressin Receptor (5)
Akt (5)
Acyltransferase (5)
DNA Alkylation (5)
Neprilysin (4)
LDL (4)
CAT (4)
TRP/TRPV Channel (4)
STAT (4)
SGK (4)
GABA Receptor (4)
Antibiotic (4)
NOS (4)
Dopamine Receptor (4)
ribosome (4)
PI3K (4)
GluR (4)
GPCR19 (4)
Acetyl-CoA Carboxylase (3)
OAT (3)
Antioxidant (3)
Nrf2 (3)
Topoisomerase (3)
Annexin A (3)
Thyroid hormone receptor(THR) (3)
TAM Receptor (3)
Norepinephrine (3)
Src (3)
Reactive Oxygen Species (3)
NADPH-oxidase (3)
Serine/threonin kinase (3)
Carboxypeptidase(CPG2) (3)
Xanthine Oxidase (3)
Decarboxylase (3)
Ferroptosis (3)
ATP Citrate Lyase (3)
BCL (3)
ABC (3)
c-Met/HGFR (3)
Chloride channel (3)
CCR (3)
Integrin (3)
Endothelin Receptor (3)
Glutathione Peroxidase (2)
Aurora Kinase (2)
P2 Receptor (2)
p53 (2)
Parasite (2)
PARP (2)
PDK (2)
PERK (2)
Androgen Receptor (2)
BACE (2)
Electron transport (2)
Amino Acids and Derivatives (2)
Epigenetic Reader Domain (2)
Adiponectin receptor (2)
Rho (2)
EGFR (2)
Adenosine Receptor (2)
S6 Kinase (2)
Sigma receptor (2)
SIK (2)
CaMK (2)
TGF-beta/Smad (2)
c-RET (2)
cell cycle arrest (2)
Glutathione reductase (2)
JAK (2)
GR (2)
Hexokinase (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
Antiviral (2)
LTR (2)
MEK (2)
Antifungal (2)
HSV (2)
ASK (2)
Histone Demethylase (2)
MLK (2)
Neurokinin receptor (2)
NPC1L1 (2)
FLT (2)
Hedgehog/Smoothened (1)
CPT (1)
GST (1)
Bradykinin Receptor (1)
Mdm2 (1)
GSNOR (1)
CXCR (1)
Stearoyl-CoA Desaturase (SCD) (1)
stilbene oxidase (1)
Syk (1)
CSF-1R (1)
Telomerase (1)
LRRK2 (1)
Thioredoxin (1)
LPA Receptor (1)
TLR (1)
DNA (1)
IGF-1R (1)
c-Kit (1)
Transaminase (1)
aconitase (1)
cholecystokinin (1)
Trk receptor (1)
OX Receptor (1)
CGRP Receptor (1)
Tyrosine Kinases (1)
CFTR (1)
c-Fms (1)
iGluR (1)
PDGFR (1)
CaSR (1)
Melatonin Receptor (1)
DNA gyrase (1)
PED (1)
Epoxide Hydrolase (1)
ATM/ATR (1)
P-gp (1)
Na-K-Cl cotransporter (1)
Histone Acetylation (1)
Free radical scavengers (1)
Isocitrate Dehydrogenase (IDH) (1)
Pim (1)
PAK (1)
FABP (1)
N-Acetylglucosaminyltransferase (1)
Platelet aggregation (1)
Gap Junction Protein (1)
ALK (1)
MT Receptor (1)
Anion Exchanger (1)
Proton pump (1)
Arginase (1)
RAR/RXR (1)
Bcr-Abl (1)
advanced glycation end products (1)
NMDAR (1)
Monocarboxylate transporter (1)
Hydrogenase (1)
GRK (1)
NO Synthase (1)
Beta Amyloid (1)
DNA-PK (1)
IAP (1)
BMI-1 (1)
DNA Methyltransferase (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE