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Pack Size | Price | Availability | Quantity |
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5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Neuropeptide W-23 (human) (NPW-23) TFA, representing the active form of Neuropeptide W, functions as an endogenous agonist for both NPBW1 (GPR7) and NPBW2 (GPR8) receptors [1]. |
In vitro | Neuropeptide W-23 (human) (NPW-23) enhances the L-type calcium current (I Ca,L) in human embryonic kidney 293 cells and vascular smooth muscle cells (VSMCs) through the activation of G protein-coupled receptor 7 (GPR7) [1]. |
In vivo | Neuropeptide W-23 (human) (NPW-23) administered intracerebroventricularly (i.c.v.) at doses of 0.3-3.0 nM in a volume of 2 μL enhances total behavioral activities such as locomotion and grooming in conscious rats [2]. At higher concentrations of 2-8 nM and a volume of 10 μL, NPW-23 exhibits an anorexigenic effect, suppressing food intake in rats [3]. |
Alias | NPW-23 TFA |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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