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Neuropeptide W-23 (human) (TFA)
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Catalog No. T81680
Alias NPW-23 TFA
Neuropeptide W-23 (human) (NPW-23) TFA, representing the active form of Neuropeptide W, functions as an endogenous agonist for both NPBW1 (GPR7) and NPBW2 (GPR8) receptors [1].
Neuropeptide W-23 (human) (TFA)
Neuropeptide W-23 (human) (TFA)
😃Good
Catalog No. T81680Alias NPW-23 TFA
Neuropeptide W-23 (human) (NPW-23) TFA, representing the active form of Neuropeptide W, functions as an endogenous agonist for both NPBW1 (GPR7) and NPBW2 (GPR8) receptors [1].
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Product Introduction
Bioactivity
Chemical Properties
| Description | Neuropeptide W-23 (human) (NPW-23) TFA, representing the active form of Neuropeptide W, functions as an endogenous agonist for both NPBW1 (GPR7) and NPBW2 (GPR8) receptors [1]. |
| In vitro | Neuropeptide W-23 (human) (NPW-23) enhances L-type calcium current (I Ca,L) in human embryonic kidney 293 cells and vascular smooth muscle cells (VSMCs) by activating G protein-coupled receptor 7 (GPR7) [1]. |
| In vivo | Neuropeptide W-23 (human) (NPW-23), when administered intracerebroventricularly (i.c.v.) at doses of 0.3-3.0 nM in a volume of 2 μL, enhances total behavioral activities such as locomotion and grooming in conscious rats [2]. At higher concentrations of 2-8 nM in a volume of 10 μL, NPW-23 exhibits an anorexigenic effect, suppressing food intake in rats [3]. |
| Alias | NPW-23 TFA |
Storage & Solubility Information
| Storage | keep away from moisture | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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