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Caloxin 2A1 is an inhibitor peptide of the plasma membrane Ca 2+-ATPase (PMCA) responsible for extracellular signaling. Importantly, Caloxin 2A1 has no impact on the basal Mg 2+-ATPase or Na+-K+-ATPase activities.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | Caloxin 2A1 is an inhibitor peptide of the plasma membrane Ca 2+-ATPase (PMCA) responsible for extracellular signaling. Importantly, Caloxin 2A1 has no impact on the basal Mg 2+-ATPase or Na+-K+-ATPase activities. |
In vitro | Caloxin 2A1 selectively inhibits the Ca2+-Mg2+-ATPase activity in human erythrocyte leaky ghosts while maintaining no impact on the basal Mg2+-ATPase or Na+-K+-ATPase activity in the same cells, or on the Ca2+-Mg2+-ATPase activity in skeletal muscle sarcoplasmic reticulum. Additionally, it hampers the Ca2+-dependent synthesis of the 140-kDa acid-stable acylphosphate and promotes apoptosis in airway smooth muscle cells (ASMCs). |
Molecular Weight | 1478.543 |
Formula | C64H91N19O22 |
Cas No. | 350670-85-8 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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