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[D-Pro2,D-Phe7,D-Trp9] Substance P, an analogue of Substance P, serves as an inhibitor to its parent compound and indirectly contracts the guinea-pig ileum (GPI) [1] [2].
Pack Size | Price | Availability | Quantity |
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5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | [D-Pro2,D-Phe7,D-Trp9] Substance P, an analogue of Substance P, serves as an inhibitor to its parent compound and indirectly contracts the guinea-pig ileum (GPI) [1] [2]. |
In vitro | '[D-Pro2, D-Phe7, D-Trp9] Substance P (10-100 μM; 2 min or 10 min) elicited dose-dependent contractions in both the guinea pig ileum and the rabbit external jugular vein [1].' |
In vivo | Administering '[D-Pro2,D-Phe7,D-Trp9] Substance P' intravenously at a dosage of 1-2 mg/kg once effectively inhibits Substance P-induced salivary secretion in rats. Within a lower dosage range of 1-1.5 mg/kg, it modestly elevates blood pressure. |
Molecular Weight | 1476.79 |
Formula | C72H105N19O13S |
Cas No. | 77275-70-8 |
Storage | keep away from moisture | Shipping with blue ice. |
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