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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $46 | In Stock | |
10 mg | $74 | In Stock | |
25 mg | $115 | In Stock | |
50 mg | $156 | In Stock | |
100 mg | $238 | In Stock | |
1 mL x 10 mM (in DMSO) | $63 | In Stock |
Description | Thyrotropin-Releasing Hormone (TRH), Free Acid (TRH-OH), induces various thyroidal and non-thyroidal effects, most notably the feedback regulation of thyroid hormone levels. |
In vitro | Thyrotropin-releasing-hormone (TRH) stimulated the release of newly synthesized GH and PRL, but not thyroid-stimulating hormone. In addition, TRH stimulated a dose-related increase in the release of newly synthesized GH and PRL at 10(-9) to 10(-7) M. Cyclo(His-Pro) stimulated the release of newly synthesized GH dose- dependently. TRH, cyclo(His-Pro), and hGHRH stimulated GH synthesis, while SRIF inhibited this at 10(-7) M. The release of newly synthesized PRL into culture medium was also stimulated by TRH and hGHRH, but inhibited by SRIF. PRL synthesis was not affected by TRH-OH and cyclo(His-Pro). Intracellular contents of GH and PRL in the pituitary did not change significantly.TRH plays an important role in both GH and PRL synthesis and release[1]. |
Alias | TRH-OH |
Molecular Weight | 363.37 |
Formula | C16H21N5O5 |
Cas No. | 24769-58-2 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 11 mg/mL (30.27 mM) ![]() | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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