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Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 μg | $294 | 35 days | |
1 mg | $570 | 35 days | |
5 mg | $2,230 | 35 days |
Description | Antileukinate is a synthetic hexapeptide with an acetylated amino terminus and an amidated carboxyl terminus that inhibits the binding of CXC chemokines to the chemokine receptor CXCR2. It inhibits IL-8 binding to neutrophils (Ki = 2.7-13 μM), prevents neutrophil chemotaxis and β-glucuronidase release, and blocks IL-8-induced skin edema in rabbits. At 53 mg/kg, antileukinate has been shown to protect mice against acute pancreatitis and associated lung injury. |
Molecular Weight | 1003.19 |
Formula | C45H66N18O7S |
Cas No. | 138559-60-1 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMF: 1 mg/mL PBS (pH 7.2): 2 mg/mL DMSO: 5 mg/mL |
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