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Oxytocin antiparallel dimer TFA is a homo peptide dimer connected by a disulfide bridge, exhibiting activities similar to oxytocin and vasopressin but with reduced toxicity [1] [2].
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Description | Oxytocin antiparallel dimer TFA is a homo peptide dimer connected by a disulfide bridge, exhibiting activities similar to oxytocin and vasopressin but with reduced toxicity [1] [2]. |
In vitro | The biological activity of parallel and antiparallel, homodimeric/heterodimeric disulfide-linked dimers of oxytocin and deamino-oxytocin ranges from 0.2% to 6% of that of oxytocin [1]. |
In vivo | Oxytocin dimer, when administered intravenously (静脉注射) as a single dose (单剂量), exhibits lower acute toxicity in rats compared to oxytocin, with an LD50 of 43 mg/kg versus 25 mg/kg [2]. |
Storage | keep away from moisture | Shipping with blue ice. |
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