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Cyclosporin B

Name: Cyclosporin B
Brand: TargetMol
SKU: T19848
Rating: 4.5 (1 reviews)

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Catalog No. T19848Cas No. 63775-95-1

Alias Antibiotic S 7481F2, 7-L-Alanine-cyclosporin A

Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity.

Cyclosporin B

😃Good

Catalog No. T19848Alias Antibiotic S 7481F2, 7-L-Alanine-cyclosporin ACas No. 63775-95-1

Pack Size	Price	Availability
1 mg	$115	35 days
5 mg	$345	35 days
10 mg	$575	35 days
25 mg	$984	35 days

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Product Introduction

Bioactivity

Description	Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also
Alias	Antibiotic S 7481F2, 7-L-Alanine-cyclosporin A

Chemical Properties

Molecular Weight	1188.58
Formula	C₆₁H₁₀₉N₁₁O₁₂
Cas No.	63775-95-1
Relative Density.	1.019 g/cm3 (Predicted)

Storage & Solubility Information

Storage	keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO: Soluble

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

Cyclosporin B