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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $205 | In Stock | |
5 mg | $497 | In Stock | |
10 mg | $738 | In Stock | |
25 mg | $1,150 | In Stock | |
50 mg | $1,550 | In Stock | |
100 mg | $1,980 | In Stock | |
500 mg | $4,190 | In Stock |
Description | Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. |
In vitro | An orphan G protein-coupled receptor (SLC-1/GPR24) has been identified as a receptor for MCH (MCHR1). MCHR2 has higher protein sequence homology to MCHR1 than any other G protein-coupled receptor. MCHR2 is specifically activated by nanomolar concentrations of MCH, binds to MCH with high affinity, and signals through Gq protein[1]. |
In vivo | Melanin Concentrating Hormone stimulates appetite. Continuous infusion of Melanin Concentrating Hormone into the ventricular system increases food intake for 7-8 days[2]. Intracerebroventricular infusion of Melanin Concentrating Hormone (10 μg/day) causes a slight but significant increase in body weight in mice maintained on the regular diet. Chronic stimulation of the brain Melanin Concentrating Hormone system could cause obesity in mice[3]. |
Alias | MCH (salmon), Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) |
Molecular Weight | 2157 |
Formula | C91H143N27O26S4 |
Cas No. |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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