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SpHistin

Catalog No. T80361

SpHistin, an antimicrobial peptide (AMP), binds to lipopolysaccharide (LPS) and permeabilizes the bacterial membrane. In combination with Rifampicin and Azithromycin, it facilitates increased intracellular uptake of these antibiotics, thereby enhancing their collective bactericidal efficacy against Pseudomonas aeruginosa [1].

SpHistin

SpHistin

Catalog No. T80361
SpHistin, an antimicrobial peptide (AMP), binds to lipopolysaccharide (LPS) and permeabilizes the bacterial membrane. In combination with Rifampicin and Azithromycin, it facilitates increased intracellular uptake of these antibiotics, thereby enhancing their collective bactericidal efficacy against Pseudomonas aeruginosa [1].
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Product Introduction

Bioactivity
Description
SpHistin, an antimicrobial peptide (AMP), binds to lipopolysaccharide (LPS) and permeabilizes the bacterial membrane. In combination with Rifampicin and Azithromycin, it facilitates increased intracellular uptake of these antibiotics, thereby enhancing their collective bactericidal efficacy against Pseudomonas aeruginosa [1].
Chemical Properties
Molecular Weight3943.59
FormulaC170H293N61O45S
Storage & Solubility Information
Storagekeep away from moisture | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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