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G7-18NATE, a peptide inhibitor of Grb7, exhibits micromolar affinity (K D = 18.1 μM) for binding to the Grb7-SH2 domain. It effectively inhibits cell proliferation, motility, invasion, and 3D culture formation in various cancer cell lines [1] [2].
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50 mg | Inquiry | Inquiry |
Description | G7-18NATE, a peptide inhibitor of Grb7, exhibits micromolar affinity (K D = 18.1 μM) for binding to the Grb7-SH2 domain. It effectively inhibits cell proliferation, motility, invasion, and 3D culture formation in various cancer cell lines [1] [2]. |
In vitro | G7-18NATE (10 μM, 24 h) inhibits the migration of MDA-MB-468 cells [2]. |
Molecular Weight | 1417.5 |
Formula | C67H80N14O19S |
Cas No. | 936728-13-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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