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Aviptadil Acetate

Name: Aviptadil Acetate
Brand: TargetMol
SKU: TP1016L
Price: 84 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TP1016LCas No. 1444827-29-5

Alias Vasoactive Intestinal Peptide acetate salt

Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmonary fibrosis, pulmonary hypertension (PAH), and respiratory failure caused by SARS-CoV-2.

Aviptadil Acetate

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Purity: 100%

Catalog No. TP1016LAlias Vasoactive Intestinal Peptide acetate saltCas No. 1444827-29-5

Pack Size	Price	Availability
1 mg	$84	In Stock
5 mg	$178	In Stock
10 mg	$289	In Stock
25 mg	$489	In Stock
50 mg	$686	In Stock
100 mg	$969	In Stock

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Purity:100%

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COA LCMS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs and platelet aggregation. Avitadil acetate can be used for research on pulmonary fibrosis, pulmonary hypertension (PAH), and respiratory failure caused by SARS-CoV-2.
In vitro	Aviptadil acetate inhibits the basal proliferation of pulmonary arterial smooth muscle cells (PASMC) and the mobilization of intracellular free calcium concentration in these cells in a dose-dependent manner[2].
In vivo	Inhaled vasoactive intestinal peptide(Aviptadil acetate ) as a local therapy to reduce the alveolar inflammation found in patients with immune checkpoint inhibitor pneumonitis[1].
Alias	Vasoactive Intestinal Peptide acetate salt

Chemical Properties

Molecular Weight	3385.9
Formula	C₁₄₇H₂₃₈N₄₄O₄₂S.C₂H₄O₂
Cas No.	1444827-29-5
Smiles	OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CC(N)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCSC)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@@H](N)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 95 mg/mL (28.06 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.2953 mL	1.4767 mL	2.9534 mL	14.7671 mL
5 mM	0.0591 mL	0.2953 mL	0.5907 mL	2.9534 mL
10 mM	0.0295 mL	0.1477 mL	0.2953 mL	1.4767 mL
20 mM	0.0148 mL	0.0738 mL	0.1477 mL	0.7384 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Aviptadil Acetate

Aviptadil Acetate

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