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Pack Size | Price | Availability | Quantity |
---|---|---|---|
250 mg | $42 | In Stock | |
500 mg | $62 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases. |
In vitro | Mechanism of Silymarin involves different biochemical reactions, such as stimulation of the rate of ribosomal RNA synthesis by stimulating the transcription of polymerase I and ribosomal RNA genes, blockage of alpha-glycoside loops toxin intake, and protection of cell membranes from free radical-induced damage. Silymarin also displays a substantial protective effect against UVB-induced canceration at different stages, possibly through its strong antioxidant properties. |
In vivo | The intravenous injection LD50 of Silymarin is 391.4 mg/kg, 70.1 mg/kg, 142.3 mg/kg for mice, rats, rabbits, respectively. |
Alias | Silybin B |
Molecular Weight | 482.44 |
Formula | C25H22O10 |
Cas No. | 65666-07-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 45 mg/mL (93.28 mM) ![]() H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 1 mg/mL (2.07 mM) | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
DMSO
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