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Molnupiravir
🥰Excellent
Catalog No. T60951Cas No. 2492423-29-5
Alias MK-4482, Lagevrio, EIDD-2801
Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability. Molnupiravir can be used in the study of COVID-19, seasonal and pandemic influenza, and has broad-spectrum antiviral activity against multiple coronaviruses and influenza viruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV.
Molnupiravir
🥰Excellent
Purity: 100%
Catalog No. T60951Alias MK-4482, Lagevrio, EIDD-2801Cas No. 2492423-29-5
Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability. Molnupiravir can be used in the study of COVID-19, seasonal and pandemic influenza, and has broad-spectrum antiviral activity against multiple coronaviruses and influenza viruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $34 | In Stock | |
| 10 mg | $55 | In Stock | |
| 25 mg | $72 | In Stock | |
| 50 mg | $122 | In Stock | |
| 100 mg | $197 | In Stock | |
| 200 mg | $372 | In Stock | |
| 500 mg | $788 | In Stock | |
| 1 g | $1,080 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $61 | In Stock |
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Purity:100%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability. Molnupiravir can be used in the study of COVID-19, seasonal and pandemic influenza, and has broad-spectrum antiviral activity against multiple coronaviruses and influenza viruses, such as SARS-CoV-2, MERS-CoV, SARS-CoV. |
| In vitro | METHODS: RD, Huh7, and Vero cells were treated with Molnupiravir (MK-4482) (EIDD-2801) (1, 10, 100 μM) for cytopathic effect (CPE) protection assay. RESULTS EIDD-2801 showed stable CPE protection potential in a dose-dependent manner in multiple cell lines infected with EV-A71 virus; the value against EV-A71 virus was 70.12±4.40μM in RD cells; 88.52±3.18μM in Vero cells, and 35.64±0.47μM in Huh7 cells. [1] |
| In vivo | METHODS: Molnupiravir (MK-4482) (EIDD-2801) (50, 150, or 500 mg/kg, orally, every 12 hours) was used to prophylactically treat mice infected with SARS-CoV and observe its effects in mice. RESULTS Molnupiravir has potent antiviral activity and is able to prevent SARS-CoV replication and disease. [1] |
| Alias | MK-4482, Lagevrio, EIDD-2801 |
| Molecular Weight | 329.31 |
| Formula | C13H19N3O7 |
| Cas No. | 2492423-29-5 |
| Smiles | CC(C)C(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc\c(=N/O)[nH]c1=O |
Storage & Solubility Information
| Storage | store at low temperature | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 40 mg/mL (121.47 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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