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α-Vitamin E

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Purity:99.89%

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COA HPLC HNMR

α-Vitamin E

Catalog No. T1648Cas No. 59-02-9

α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.

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Pack Size	Price	Availability	Quantity
50 mg	$38	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Product Introduction

Bioactivity

Description	α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
In vitro	vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide[1].
In vivo	Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation[1].
Cell Research	For in vitro cytotoxicity experiments, 1×105 TC-1 cells per well are added to 24-well plates. Eighteen hours later, tumor cells are treated with Vitamin E (0, 25, 50 μM). After 18 hours, apoptotic (Annexin V+ and 7AAD−) and necrotic (Annexin V+ and 7AAD+) cells are measured using PE Annexin V Apoptosis Detection Kit I. (Only for Reference)
Alias	Dexrabeprazole Sodium, Vitamin E, Alpha-Tocopherol, D-α-Tocopherol, 5,7,8-Trimethyltocol, (+)-alpha-Tocopherol

Chemical Properties

Molecular Weight	430.71
Formula	C29H50O2
Cas No.	59-02-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 12 mg/mL (27.86 mM)

Saline: 430.71 mg/mL (58.04 mM)

Solution Preparation Table

Saline/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3217 mL	11.6087 mL	23.2175 mL	116.0874 mL
5 mM	0.4643 mL	2.3217 mL	4.6435 mL	23.2175 mL
10 mM	0.2322 mL	1.1609 mL	2.3217 mL	11.6087 mL
20 mM	0.1161 mL	0.5804 mL	1.1609 mL	5.8044 mL

Saline

	1mg	5mg	10mg	50mg
50 mM	0.0464 mL	0.2322 mL	0.4643 mL	2.3217 mL
100 mM	0.0232 mL	0.1161 mL	0.2322 mL	1.1609 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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α-Vitamin E

α-Vitamin E