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Orally Active Compound Library

Catalog No. L9850
  Library Compound List   Excel SDF

Oral administration is the first choice for clinical drug delivery, especially for long-term use. It is also the safest, most convenient, and most economical method of drug delivery. Oral bioavailability is the percentage of the absorbed drug dose successfully passed through the mucosa of the gastrointestinal tract and entered the bloodstream through the liver, to the original given oral dose. Drugs with high oral bioavailability can achieve efficacy at lower doses and effectively reduce toxic side effects; while when bioavailability is too low, even compounds with good pharmacological activity are unable to be fully exposed and utilized at the target site, resulting in therapeutic failure or high dose with large toxic side effects, which eventually leads to drug development failure and limits the application.

TargetMol has carefully collected 2484 compounds with publicly reported oral activity that can be used for drug repurposing and development of orally active drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 2484 of orally active compounds for high-throughput screening and high-content screening.
  • Some drugs are approved or are in clinical trials with validated biological activity and safety.
  • Detailed specifications, compound structures, target information, activity descriptions, etc.
  • NMR and HPLC detection techniques to ensure high product purity.
  • All compounds are available in stock.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files
Request Library Compound List (L9850)

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..
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Library Composition

Autophagy (297)
Apoptosis (271)
Antibacterial (206)
Antibiotic (190)
5-HT Receptor (133)
Endogenous Metabolite (110)
Adrenergic Receptor (102)
Dopamine Receptor (84)
Histamine Receptor (82)
COX (77)
Parasite (64)
HIV Protease (63)
AChR (61)
DNA/RNA Synthesis (57)
VEGFR (57)
Potassium Channel (54)
EGFR (44)
Sodium Channel (44)
PDGFR (43)
P450 (43)
Calcium Channel (42)
Glucocorticoid Receptor (41)
Estrogen/progestogen Receptor (41)
c-Kit (40)
FLT (39)
SARS-CoV (39)
PDE (37)
Ferroptosis (34)
CDK (33)
Antifungal (32)
PI3K (32)
Reactive Oxygen Species (31)
Dehydrogenase (31)
JAK (30)
FGFR (29)
RAAS (29)
Topoisomerase (29)
HCV Protease (28)
Src (27)
c-Met/HGFR (26)
NF-κB (26)
Mitophagy (26)
Reverse Transcriptase (26)
Influenza Virus (25)
PPAR (25)
Estrogen Receptor/ERR (23)
Serotonin Transporter (23)
GABA Receptor (23)
BTK (23)
Proteasome (23)
Bcr-Abl (22)
mTOR (22)
GPR (21)
HBV (21)
HDAC (21)
Androgen Receptor (20)
Microtubule Associated (20)
Prostaglandin Receptor (20)
TRP/TRPV Channel (19)
p38 MAPK (19)
PARP (18)
ribosome (18)
GluR (18)
ROS (18)
Adenosine Receptor (18)
Histone Methyltransferase (18)
Tyrosine Kinases (18)
Phosphatase (18)
Raf (18)
HSV (17)
Epigenetic Reader Domain (17)
Progesterone Receptor (17)
HIF/HIF Prolyl-Hydroxylase (17)
TNF (17)
Opioid Receptor (17)
Proton pump (17)
DPP-4 (16)
ALK (16)
MEK (16)
Nucleoside Antimetabolite/Analog (16)
AChE (16)
HER (15)
Norepinephrine (15)
Trk receptor (15)
iGluR (15)
Virus Protease (14)
S1P Receptor (14)
ERK (14)
SGLT (13)
MAPK (13)
P-gp (13)
TAM Receptor (13)
Beta Amyloid (13)
c-RET (13)
LPL Receptor (13)
Transferase (13)
Thrombin (12)
ROCK (12)
MRP (12)
STAT (12)
c-Fms (12)
MMP (11)
MAO (11)
DNA gyrase (11)
Retinoid Receptor (11)
Phospholipase (11)
AMPK (11)
Aurora Kinase (11)
Syk (10)
NADPH (10)
HSP (10)
Wnt/beta-catenin (10)
Integrin (10)
Interleukin (10)
Endothelin Receptor (10)
DNA Alkylator/Crosslinker (10)
ATPase (10)
Akt (10)
CSF-1R (9)
IL Receptor (9)
HMG-CoA Reductase (9)
E1/E2/E3 Enzyme (9)
PKC (9)
CCR (9)
Caspase (9)
Guanylate cyclase (9)
Lipoxygenase (9)
Antifection (9)
TLR (9)
Mitochondrial Metabolism (9)
Fatty Acid Synthase (9)
CXCR (9)
Ras (9)
Gamma-secretase (9)
Acyltransferase (9)
ROR (8)
BCL (8)
IGF-1R (8)
PLK (8)
Factor Xa (8)
GSK-3 (8)
Complement System (8)
Thyroid hormone receptor(THR) (8)
Monoamine Oxidase (8)
ATM/ATR (7)
ABC (7)
ROS Kinase (7)
CFTR (7)
Ligand for E3 Ligase (7)
Nrf2 (7)
NO Synthase (7)
LTR (7)
Antifolate (7)
DHFR (7)
NMDAR (7)
Neurokinin receptor (7)
Beta-Secretase (7)
Hydroxylase (7)
Carbonic Anhydrase (7)
Antiviral (7)
HIF (7)
GHSR (6)
Smo (6)
Antioxidant (6)
CaMK (6)
ASK (6)
OX Receptor (6)
Leukotriene Receptor (6)
Hedgehog/Smoothened (6)
DNA Alkylation (6)
FAK (6)
DNA Methyltransferase (6)
Reductase (6)
Glutathione Peroxidase (6)
Aminopeptidase (6)
TGF-beta/Smad (6)
RSV (6)
P2Y Receptor (6)
Stearoyl-CoA Desaturase (SCD) (5)
Serine/threonin kinase (5)
Melatonin Receptor (5)
Serine Protease (5)
IAP (5)
Lipase (5)
Sigma receptor (5)
PAK (5)
Ephrin Receptor (5)
FXR (5)
IκB/IKK (5)
Isocitrate Dehydrogenase (IDH) (5)
BACE (5)
Vasopressin Receptor (5)
Casein Kinase (5)
Indoleamine 2,3-Dioxygenase (IDO) (5)
Cannabinoid Receptor (5)
NADPH-oxidase (4)
Xanthine Oxidase (4)
P2X Receptor (4)
p53 (4)
PAI-1 (4)
PGE Synthase (4)
CaSR (4)
PKA (4)
Sirtuin (4)
Aromatase (4)
Pim (4)
Monoamine Transporter (4)
MT Receptor (4)
Cysteine Protease (4)
GNRH Receptor (4)
Histone Demethylase (4)
transporter (4)
DNA-PK (4)
IRAK (4)
DNA (4)
Mdm2 (4)
Aryl Hydrocarbon Receptor (4)
PERK (3)
Porcupine (3)
JNK (3)
AhR (3)
CRM1 (3)
Neprilysin (3)
Molecular Glues (3)
DUB (3)
IFNAR (3)
Histone Acetyltransferase (3)
TOPK (3)
FAAH (3)
FLAP (3)
UGT (3)
Free radical scavengers (3)
RIP kinase (3)
Glucosidase (3)
Glucokinase (3)
Glucagon Receptor (3)
PD-1/PD-L1 (3)
Drug Metabolite (3)
PAD (3)
Chk (3)
cholecystokinin (3)
Discoidin Domain Receptor (DDR) (3)
S6 Kinase (3)
Amino Acids and Derivatives (3)
Liver X Receptor (3)
Neuropeptide Y Receptor (3)
Annexin A (3)
NOD-like Receptor (NLR) (3)
Glutathione reductase (2)
Hck (2)
Protease-activated Receptor (2)
MNK (2)
SGK (2)
BMI-1 (2)
Hexokinase (2)
Tyrosinase (2)
Acetyl-CoA Carboxylase (2)
Rho (2)
GST (2)
Adenosine deaminase (2)
STING (2)
NOD (2)
Thrombopoietin Receptor (2)
Tie-2 (2)
Telomerase (2)
Integrase (2)
Imidazoline Receptor (2)
PDK (2)
CAT (2)
CETP (2)
LDL (2)
OXPHOS (2)
PI4K (2)
LRRK2 (2)
Lipid (2)
MALT (2)
IDO (2)
Platelet aggregation (2)
advanced glycation end products (2)
Ligands for Target Protein for PROTAC (2)
CGRP Receptor (2)
Somatostatin (1)
SIK (1)
ACK (1)
Angiotensin-converting Enzyme (ACE) (1)
Adiponectin receptor (1)
Taste receptor (1)
Anti-infection (1)
Survivin (1)
Gap Junction Protein (1)
ATP Citrate Lyase (1)
Hydrogenase (1)
MLK (1)
Decarboxylase (1)
Methionine Adenosyltransferase (MAT) (1)
LPA Receptor (1)
LHRH (1)
Kinesin (1)
IRE1 (1)
DYRK (1)
Myosin (1)
Epoxide Hydrolase (1)
Haspin Kinase (1)
GRK (1)
GPX (1)
GPCR19 (1)
GlyT (1)
Glutaminase (1)
GluCls (1)
Monocarboxylate transporter (1)
Na+/Ca2+ Exchanger (1)
BCRP (1)
PAFR (1)
Pyroptosis (1)
PYK2 (1)
Bradykinin Receptor (1)
PROTAC Linker (1)
Prolyl Endopeptidase (PREP) (1)
cAMP (1)
PKM (1)
Cell wall (1)
p97 (1)
Na-K-Cl cotransporter (1)
Chloride channel (1)
OAT (1)
c-Myc (1)
NPC1L1 (1)
CRISPR/Cas9 (1)
Neurotensin Receptor (1)
NEDD8 (1)
NAMPT (1)
NOS (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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