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Search Results for " hepatocellular "

Targets

97

Compounds

44

Natural Products

84

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T22661 CHM-1 Apoptosis , Others , Microtubule Associated
CHM-1 is an inducer of apoptosis, and displays potent antitumor ability in human hepatocellular carcinoma by activation of Cdc2 kinase activity. CHM-1 inhibits tubulin polymerization in vitro and in vivo.
T22830 GYY4137 GYY 4137 morpholine salt Others
GYY4137 (GYY 4137 morpholine salt) is a novel water-soluble and slow releasing H2S donor with vasodilator and antihypertensive activity. GYY4137 also exhibits anti-inflammatory and anticancer activity.
T7008 Vacquinol-1 Vacquinol 1 JNK
Vacquinol-1 is an MKK4 activator, which rapidly and selectively induces glioma cell death.
T1785 Palbociclib PD 0332991 CDK
Palbociclib (PD 0332991) is a CDK inhibitor that inhibits CDK4 and CDK6 (IC50=11/16 nM) and is orally active. Palbociclib has anti-tumorigenic activity and has investigational potential for use in ER-positive and HER2-ne...
T6481 Droxinostat NS 41080 Apoptosis , HDAC
Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
T2562 Eltrombopag SB-497115,SB-497115-GR Thrombin
Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110).
T0334 Rosiglitazone BRL49653 Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.
T22443 Triglycidyl isocyanurate Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI Apoptosis
Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alk...
T9945 MNK8  3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione STAT
MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) is a potent STAT3 inhibitor that reduces the ability of STAT3 to bind to DNA and also has a good growth inhibition effect on liver cancer cells [1].
T6646 Rosiglitazone hydrochloride BRL-49653 HCl,Rosiglitazone HCl Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.
T6239 Palbociclib monohydrochloride PD 0332991 hydrochloride,Palbociclib hydrochloride,Palbociclib (PD-0332991) HCl CDK
Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.
T6240 Palbociclib Isethionate Palbociclib (PD0332991) Isethionate,PD 0332991 isethionate CDK
Palbociclib Isethionate (PD 0332991 isethionate) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.
T6825 Eltrombopag Olamine Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR Thrombin
Eltrombopag Olamine (Eltrombopag diethanolamine salt) is the orally active ethanolamine salt of eltrombopag, a small-molecule, nonpeptide thrombopoietin receptor agonist with megakaryopoiesis-stimulating activity. Eltrom...
T77440 Codrituzumab RG-7686,RO5137382,GC33
Codrituzumab (GC3) is a humanized antibody against the glypican-3 hepatocellular carcinoma protein that can be used in combination with sorafenib to study incurable advanced hepatocellular carcinoma (HCC).
T35367 Thioacetamide TAA Others
Thioacetamide is a hepatotoxicant used widely to induce experimental liver lesions, develops hepatocellular necrosis and subsequent inflammation (mainly M1-/M2-macrophages without neutrophil infiltration) in rats.
TQ0090 Nesbuvir HCV-796 HCV Protease
Nesbuvir is a selective hepatitis C virus (HCV) nonstructural protein 5B (NS5B) RNA-dependent polymerase inhibitor.Nesbuvir has an IC50 of 9 nM against hepatocellular carcinoma cells containing 1b HCV replicons.
T7738 H3B-6527 FGFR
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.
T4368 Miriplatin SM-11355 DNA Alkylator/Crosslinker
Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).
T13683 Epsilon-momfluorothrin Momfluorothrin, (Z,1R,3R)- Others
Epsilon-momfluorothrin (Momfluorothrin, (Z,1R,3R)-), a type I synthetic pyrethroid insecticide, exerts its insecticidal properties and triggers activation of the constitutive androstane receptor (CAR). Notably, its admin...
T22289 CFI-402257 Kinesin
CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.
T64529 MDL-800 MDL 800,MDL800 Sirtuin
MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer.
T11421 Glutaminase-IN-1 CB839 derivative transporter
Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine renal-type glutaminase (KGA) variant inhibitor, showed antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model.
T77466 Tremelimumab Ticilimumab,CP-675206 Others
Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and l...
TP1472 Tyroserleutide Others
Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo.Tyroserleutide inhibits the growth and metastasis of h...
T22424 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea Apoptosis , STAT
SC-1 is a a derivative of the multiple tyrosine kinase inhibitor sorafenib. SC-1 potently inhibits the phosphorylation of STAT3 by blocking STAT3 phosphorylation and activation, and induces apoptosis in hepatocellular ca...
T38846 Vevorisertib trihydrochloride ARQ 751 trihydrochloride Akt
Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is a selective and potent inhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3. Vevorisertib trihydrochloride is used in the study of hepat...
T15704 Lagociclovir MIV-210 HBV
Lagociclovir (MIV-210), a nucleoside analogue, is an antiviral compound available for the treatment of HBV82 that inhibits the replication of wild-type hepatitis B virus (HBV) in human hepatocellular carcinoma cell lines...
T76858 Ascrinvacumab PF-03446962 ALK , TGF-beta/Smad
Ascrinvacumab (PF-03446962) is a highly humanized IgG2 monoclonal antibody against ALK-1. Ascrinvacumab has a Kd value of 7 nM for human ALK1. Ascrinvacumab has an inhibitory effect on TGF-β and can be used to study hepa...
T15367 Gadoxetate Disodium Gd-EOB-DTPA Disodium,ZK 139834 Others
Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary sy...
T77149 Cobolimab TSR-022,GSK4069889 Others
Cobolimab (TSR-022) is a potent monoclonal antibody to TIM-3. Cobolimab induces internalization of TIM-3 with an IC50 value of 0.4464 nM. Cobolimab has antitumor activity and can be used to study advanced/metastatic mela...
T9842 5-HT2B antagonist-1
5-HT2B antagonist-1 is an orally active 5-HT2B receptor antagonist with an IC 50 of 33.4 nM. It can be used in studies of diseases characterized by 5-HT2B receptor signaling, such as hepatocellular carcinoma, cardiovascu...
T21297 Miriplatin hydrate SM-11355 (hydrate),Miripla,Miriplatin,SM 11355,SM11355,SM-11355,Miriplatin hydrate DNA Alkylation
Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin hydrate is a lipophilic platinum complex that can ...
T11126 Durvalumab MEDI 4736 PD-1/PD-L1
Durvalumab (MEDI 4736) is a humanized monoclonal antibody targeting PD-L1. It can block the interaction of PD-L1 with PD-1 and CD80, with IC50 values of 0.1 and 0.04 nM, respectively. Durvalumab is often used in combinat...
T7709 (E/Z)-GSK5182 GSK5182(Z/E) Estrogen/progestogen Receptor , ROS
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating ...
T62491 STAT3-IN-13 STAT
STAT3-IN-13 is a potent STAT3 inhibitor.STAT3-IN-13 has antiproliferative and anticancer activity and acts by binding to the structural domain of STAT3 SH2.STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705, which in...
T77651 Tubulin polymerization-IN-47 Microtubule Associated
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 an...
T16538 PIN1 inhibitor API-1 Others
PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, th...
T3226 Paritaprevir ABT-450,Veruprevir HCV Protease
Paritaprevir (ABT-450) is an orally bioavailable, synthetic acylsulfonamide inhibitor of the hepatitis C virus (HCV) protease complex comprised of non-structural protein 3 and 4A (NS3/NS4A), with potential activity again...
T28982 TLC 388 TLC-388,TLC388
TLC 388, a DNA topoisomerase I inhibitor, is used potentially for the treatment of Renal carcinoma and Hepatocellular carcinoma
T34829 Tetrazanbigen TNBG
Tetrazanbigen is an inducer of S phase arrest and apoptosis in hepatocellular carcinoma QGY-7701.
T24699 R1498 R-1498,R 1498
R1498 is an inhibitor of cyclin-dependent kinase 2. It also acts by targeting angiogenesis and mitosis pathways. It is well-tolerated and orally active for hepatocellular carcinoma and gastric cancer treatment.
T68464 PABA/NO
PABA/NO is a novel glutathione-S-transferase-p-activated nitric oxide donor, inhibiting proliferation and inducing apoptosis by targeting PI3K/AKT/mTOR and MEK/ERK pathways in hepatocellular carcinoma cells.
T37425 FGFR4-IN-5 FGFR4-IN-5
FGFR4-IN-5, a covalent FGFR4 inhibitor, demonstrates potency and selectivity with an IC50 value of 6.5 nM. Exhibiting significant in vivo anti-tumor activity, it is applicable for research in hepatocellular carcinoma [1]...
T60277 2-Acetamidofluorene
2-Acetamidofluorene, a potent carcinogen, is utilized for the induction of hepatocellular carcinoma (HCC) and multiple primary tumors [1] [2].
T63653 AKT-IN-11
AKT-IN-11 is one of the most potent antibacterial agents against human hepatocellular carcinoma Bel-7402 cell line (IC50: 1.15 μM).
T70318 AMG-337 monohydrate
AMG-337 monohydrate is a highly selective small molecule MET inhibitor. Aberrant hepatocyte growth factor (HGF)/MET signaling has been implicated in hepatocarcinogenesis, suggesting that MET may serve as an attractive th...
T62151 CHNQD-01255
CHNQD-01255 is an orally active inhibitor of Arf-GEFs that is effective against hepatocellular carcinoma (HCC).
T77102 Nofazinlimab
Nofazinlimab (CS1003), a humanized IgG4 anti-PD-1 monoclonal antibody, is employed in research for unresectable hepatocellular carcinoma (uHCC) [1].
T61597 Nampt-IN-7
Nampt-IN-7, also known as compound GF8, is a powerful NAMPT inhibitor exhibiting an IC50 value of 7.31 μM. It possesses significant cytotoxic effects against the human HepG2 hepatocellular carcinoma cell line, with an IC...
T63662 FGFR4-IN-9
FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.

Compounds

CHM-1
T22661
Synonym:
Target: Apoptosis, Others, Microtubule Associated
GYY4137
T22830
Synonym: GYY 4137 morpholine salt
Target: Others
Vacquinol-1
T7008
Synonym: Vacquinol 1
Target: JNK
Palbociclib
T1785
Synonym: PD 0332991
Target: CDK
Droxinostat
T6481
Synonym: NS 41080
Target: Apoptosis, HDAC
Eltrombopag
T2562
Synonym: SB-497115,SB-497115-GR
Target: Thrombin
Rosiglitazone
T0334
Synonym: BRL49653
Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy
Triglycidyl isocyanurate
T22443
Synonym: Tris(2,3-epoxypropyl) Isocyanurate,Teroxirone,TGIC,TGI
Target: Apoptosis
MNK8 
T9945
Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione
Target: STAT
Rosiglitazone hydrochloride
T6646
Synonym: BRL-49653 HCl,Rosiglitazone HCl
Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy
Palbociclib monohydrochloride
T6239
Synonym: PD 0332991 hydrochloride,Palbociclib hydrochloride,Palbociclib (PD-0332991) HCl
Target: CDK
Palbociclib Isethionate
T6240
Synonym: Palbociclib (PD0332991) Isethionate,PD 0332991 isethionate
Target: CDK
Eltrombopag Olamine
T6825
Synonym: Promacta Olamine,Revolade,Eltrombopag diethanolamine salt,SB497115,SB-497115GR
Target: Thrombin
Codrituzumab
T77440
Synonym: RG-7686,RO5137382,GC33
Target:
Thioacetamide
T35367
Synonym: TAA
Target: Others
Nesbuvir
TQ0090
Synonym: HCV-796
Target: HCV Protease
H3B-6527
T7738
Synonym:
Target: FGFR
Miriplatin
T4368
Synonym: SM-11355
Target: DNA Alkylator/Crosslinker
Epsilon-momfluorothrin
T13683
Synonym: Momfluorothrin, (Z,1R,3R)-
Target: Others
CFI-402257
T22289
Synonym:
Target: Kinesin
MDL-800
T64529
Synonym: MDL 800,MDL800
Target: Sirtuin
Glutaminase-IN-1
T11421
Synonym: CB839 derivative
Target: transporter
Tremelimumab
T77466
Synonym: Ticilimumab,CP-675206
Target: Others
Tyroserleutide
TP1472
Synonym:
Target: Others
1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
T22424
Synonym:
Target: Apoptosis, STAT
Vevorisertib trihydrochloride
T38846
Synonym: ARQ 751 trihydrochloride
Target: Akt
Lagociclovir
T15704
Synonym: MIV-210
Target: HBV
Ascrinvacumab
T76858
Synonym: PF-03446962
Target: ALK, TGF-beta/Smad
Gadoxetate Disodium
T15367
Synonym: Gd-EOB-DTPA Disodium,ZK 139834
Target: Others
Cobolimab
T77149
Synonym: TSR-022,GSK4069889
Target: Others
5-HT2B antagonist-1
T9842
Synonym:
Target:
Miriplatin hydrate
T21297
Synonym: SM-11355 (hydrate),Miripla,Miriplatin,SM 11355,SM11355,SM-11355,Miriplatin hydrate
Target: DNA Alkylation
Durvalumab
T11126
Synonym: MEDI 4736
Target: PD-1/PD-L1
(E/Z)-GSK5182
T7709
Synonym: GSK5182(Z/E)
Target: Estrogen/progestogen Receptor, ROS
STAT3-IN-13
T62491
Synonym:
Target: STAT
Tubulin polymerization-IN-47
T77651
Synonym:
Target: Microtubule Associated
PIN1 inhibitor API-1
T16538
Synonym:
Target: Others
Paritaprevir
T3226
Synonym: ABT-450,Veruprevir
Target: HCV Protease
TLC 388
T28982
Synonym: TLC-388,TLC388
Target:
Tetrazanbigen
T34829
Synonym: TNBG
Target:
R1498
T24699
Synonym: R-1498,R 1498
Target:
PABA/NO
T68464
Synonym:
Target:
FGFR4-IN-5
T37425
Synonym: FGFR4-IN-5
Target:
2-Acetamidofluorene
T60277
Synonym:
Target:
AKT-IN-11
T63653
Synonym:
Target:
AMG-337 monohydrate
T70318
Synonym:
Target:
CHNQD-01255
T62151
Synonym:
Target:
Nofazinlimab
T77102
Synonym:
Target:
Nampt-IN-7
T61597
Synonym:
Target:
FGFR4-IN-9
T63662
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
TN1968 N-​Feruloyloctopamine N-Feruloyloctopamine p38 MAPK , Akt
N-Feruloyloctopamine is a natural product.
T6670 Silymarin Silybin B SARS-CoV
Silymarin (Silybin B) (Silybin B) is a polyphenolic flavonoid that extracts from the milk thistle or seeds of Silybum marianum. It is used in the prevention and treatment of liver diseases.
T13741 Isoviolanthin Others
Isoviolanthin reduces the migratory and invasive capacities of TGF-β1-treated HCC cells without cytotoxic effects on normal live cells and has potential as a therapeutic agent for the treatment of advanced-stage metastat...
TN1019 Beta-mangostin β-Mangostin Apoptosis , Antibacterial , Parasite
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculo...
TN2147 Retrorsine P450 , OCT
Retrorsine selectively inhibits hepatocyte proliferation and following liver injury evokes small hepatocyte-like progenitor cells. Retrorsine can be used for the research of hepatocellular injury.
T3673 Mollugin Rubimaillin HER , JAK
Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upr...
TN7217 4,6-Benzilidine-D-Glucose
4,6-Benzilidine-D-Glucose is a clinical antitumor compound showing antitumor activity in rats with chemically induced hepatocellular carcinoma.
TN1644 Flavanomarein Others
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea...
T5S0506 Rotundic acid Rutundic acid Apoptosis , Others , p38 MAPK , Akt , mTOR
Rotundic acid (Rutundic acid), a natural compound, exhibit cytotoxic activities toward human hepatocellular carcinoma (HepG2), malignant melanoma (A375), SCLC (NCI-H446), breast cancer (MCF-7), and colon cancer (HT-29) c...
T6S0117 Avicularin Fenicularin ERK
Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...
T2S0837 Astragalus Polysacharin 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,89250-26-0 TAM Receptor
2-(Chloromethyl)-4-(4-nitrophenyl)thiazole is a natural product derived from Astragalus propinquus.2-(Chloromethyl)-4-(4-nitrophenyl)thiazole exhibits anticancer activity. 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole posse...
T4868 Gamma-Linolenic acid gamolenic acid,γ-Linolenic acid Endogenous Metabolite
gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced r...
TN6694 5,6-Benzoflavone β-Naphthoflavone,beta-NF Antioxidant
5,6-Benzoflavone (β-Naphthoflavone) is an exogenous ligand for the aryl hydrocarbon receptor, which disrupts zinc homeostasis in human hepatocellular carcinoma HepG2 cells. 5,6-Benzoflavone (β-Naphthoflavone) possesses a...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T6S1699 Shogaol [6]-Shogaol,6-Shogaol Lipoxygenase , Autophagy
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the f...
T4S0145 Corylifol A Corylinin hCE , STAT , UGT
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...
T5S2343 Acetylshikonin Acetyl shikonin Others , P450 , AChE
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang...
T24744 Rubone
Rubone is the tumor suppressor miRNA-34a modulator that acts by inhibiting the growth of hepatocellular carcinoma.
T23774 Bauerenol NSC 147745,Baurenol
Bauerenol is a triterpenoid from Indian Suregada angustifolia. It also induces reactive oxygen species-mediated P38MAPK activation and apoptosis in human hepatocellular carcinoma cells.
TN4715 Ophiopogonanone F Others
Ophiopogonanone F can be used for preparing a drug for resisting hepatocellular injury.
TN1156 (-)-Curine p53
(-)-Curine can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status.
TN1200 19-Oxocinobufotalin Others
19-Oxocinobufotalin 3-adipoylarginine ester shows significant inhibition effect against human hepatocellular carcinoma cell line SMMC-7721 in vitro.
TN1013 Cucurbitacin D IL Receptor , JNK , STAT
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.
TN3931 Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid ERK , BCL , p38 MAPK , NF-κB , Caspase , JNK , p53
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα.
T27282 Erucin AR 1G3839,AR-1G3839,CCRIS-9056,CCRIS9056,AR1G3839,CCRIS 9056
Erucin is a sulforaphane analog found in cruciferous vegtables. Erucin is a telomerase inhibitor. It induces phase II enzyme activity, suppresses cellular proliferation in hepatocellular carcinoma cells, prevents 6-OHDA-...
TN4496 Marginatoxin Caspase , Fas/FasL
Marginatoxin may be a promising chemopreventive agent for treating hepatocellular carcinoma, it induces human hepatoma BEL-7402 cells apoptosis in vitro and in vivo via activation of Fas/FasL-mediated apoptotic pathway.
TN3740 Cyclocommunol PAFR
Cyclocommunol exhibits cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines. It also shows strong inhibition of arachidonic acid (AA)- and collagen-induced pla...
TN6054 Norglaucine hydrochloride
(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and...
T28122 Myrtenal NSC-54384,NSC 54384,NSC54384,Benihinal
Myrtenal is a natural monoterpene. It is found to attenuate diethylnitrosamine-induced hepatocellular carcinoma in rats by stabilizing intrinsic antioxidants and modulating apoptotic and anti-apoptotic cascades. Myrtenal...
TN1549 Damnacanthal IL Receptor , Akt , Syk
Damnacanthal possesses anti-cancer, immunomodulatory, antinociceptive and anti-inflammatory actions, it can treat or prevent hepatocellular carcinoma through its inhibitory effects on the HGF/c-Met axis.
TN1728 Hellebrigenin PARP , Akt , CDK
Hellebrigenin has anti-hepatoma activities, it induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Hellebrigenin exhibites moderate to strong activity against ...
T75454 Penicitide A
Penicitide A, a marine secondary metabolite, demonstrates moderate cytotoxic effects against the pathogen A. brassicae and the human hepatocellular liver carcinoma (HepG2) cell line [1].
TN1464 Camellianin A RAAS
Camellianin A has anticancer activity, it can inhibit the proliferation of the human hepatocellular liver carcinoma Hep G2 and human breast adenocarcinoma MCF-7 cell lines in a dose-dependent manner and induce the signif...
T3425 Polyphyllin G Polyphyllin VII,Polyphyllin VII,Y-0166 Others
Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocel...
T75637 Demethylcantharidate disodium
Demethylcantharidate disodium, an endogenous metabolite, demonstrates significant anticancer efficacy against various cancers by inducing apoptosis in hepatocellular carcinoma cells through endoplasmic reticulum (ER) str...
TN1617 Ergosta-4,6,8(14),22-tetraen-3-one BCL , Caspase , p53
Ergosta-4,6,8(14),22-tetraen-3-one has cytotoxic activity against human gastric cancer cell, it can induce G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells, these results would be useful...
TN1646 Flemiphilippinin A Others
Flemiphilippin A has antioxidant activity, it shows DPPH radical scavenging activity with effective half maximal concentration (EC50) of 18.36 ug/mL. Flemiphilippinin A (5 ug/mL) exhibits some level of antitumor activity...
TN5050 Sprengerinin C NADPH-oxidase , VEGFR , p38 MAPK , ROS , Akt , PI3K , mTOR , p53
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can strongly suppress tumor angiogenesis in human umbilical vein ...
TN6458 Acetylshikonin
Acetylshikonin can effectively inhibit tumor cells, it can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. Acety...
T64246 Cinchonine monohydrochloride hydrate
Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural and potent antimalarial agent and an inhibitor of human platelet aggregation. apoptosis in human hepatocellular carcinoma cells and inhibits adipogen...
TN4113 Garcinone E Antifection
Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent...
T81030 Tauro-β-muricholic acid TβMCA FXR
Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, acts as a competitive and reversible FXR antagonist (IC 50 = 40 μM) and exhibits antiapoptotic effects by inhibiting bile acid-induced hepatocellular apoptosi...
T37452 Stephacidin B
Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, includ...
TN4300 Isojacareubin MAPK , PKC , Antifection
Isojacareubin displays potent activity against H. pylori HP40 clinical isolate with MIC 23.9 uM, which is approximately two times greater than that of the standard drug amoxicillin. Isojacareubin is a potent inhibitor of...

Natural Products

N-​Feruloyloctopamine
TN1968
Synonym: N-Feruloyloctopamine
Target: p38 MAPK, Akt
Silymarin
T6670
Synonym: Silybin B
Target: SARS-CoV
Isoviolanthin
T13741
Synonym:
Target: Others
Beta-mangostin
TN1019
Synonym: β-Mangostin
Target: Apoptosis, Antibacterial, Parasite
Retrorsine
TN2147
Synonym:
Target: P450, OCT
Mollugin
T3673
Synonym: Rubimaillin
Target: HER, JAK
4,6-Benzilidine-D-Glucose
TN7217
Synonym:
Target:
Flavanomarein
TN1644
Synonym:
Target: Others
Rotundic acid
T5S0506
Synonym: Rutundic acid
Target: Apoptosis, Others, p38 MAPK, Akt, mTOR
Avicularin
T6S0117
Synonym: Fenicularin
Target: ERK
Astragalus Polysacharin
T2S0837
Synonym: 2-(Chloromethyl)-4-(4-nitrophenyl)thiazole,89250-26-0
Target: TAM Receptor
gamma-Linolenic acid
T4868
Synonym: gamolenic acid,γ-Linolenic acid
Target: Endogenous Metabolite
5,6-Benzoflavone
TN6694
Synonym: β-Naphthoflavone,beta-NF
Target: Antioxidant
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
Shogaol
T6S1699
Synonym: [6]-Shogaol,6-Shogaol
Target: Lipoxygenase, Autophagy
Corylifol A
T4S0145
Synonym: Corylinin
Target: hCE, STAT, UGT
Acetylshikonin
T5S2343
Synonym: Acetyl shikonin
Target: Others, P450, AChE
Rubone
T24744
Synonym:
Target:
Bauerenol
T23774
Synonym: NSC 147745,Baurenol
Target:
Ophiopogonanone F
TN4715
Synonym:
Target: Others
(-)-Curine
TN1156
Synonym:
Target: p53
19-Oxocinobufotalin
TN1200
Synonym:
Target: Others
Cucurbitacin D
TN1013
Synonym:
Target: IL Receptor, JNK, STAT
ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
TN3931
Synonym:
Target: ERK, BCL, p38 MAPK, NF-κB, Caspase, JNK, p53
Erucin
T27282
Synonym: AR 1G3839,AR-1G3839,CCRIS-9056,CCRIS9056,AR1G3839,CCRIS 9056
Target:
Marginatoxin
TN4496
Synonym:
Target: Caspase, Fas/FasL
Cyclocommunol
TN3740
Synonym:
Target: PAFR
Norglaucine hydrochloride
TN6054
Synonym:
Target:
Myrtenal
T28122
Synonym: NSC-54384,NSC 54384,NSC54384,Benihinal
Target:
Damnacanthal
TN1549
Synonym:
Target: IL Receptor, Akt, Syk
Hellebrigenin
TN1728
Synonym:
Target: PARP, Akt, CDK
Penicitide A
T75454
Synonym:
Target:
Camellianin A
TN1464
Synonym:
Target: RAAS
Polyphyllin G
T3425
Synonym: Polyphyllin VII,Polyphyllin VII,Y-0166
Target: Others
Demethylcantharidate disodium
T75637
Synonym:
Target:
Ergosta-4,6,8(14),22-tetraen-3-one
TN1617
Synonym:
Target: BCL, Caspase, p53
Flemiphilippinin A
TN1646
Synonym:
Target: Others
Sprengerinin C
TN5050
Synonym:
Target: NADPH-oxidase, VEGFR, p38 MAPK, ROS, Akt, PI3K, mTOR, p53
Acetylshikonin
TN6458
Synonym:
Target:
Cinchonine monohydrochloride hydrate
T64246
Synonym:
Target:
Garcinone E
TN4113
Synonym:
Target: Antifection
Tauro-β-muricholic acid
T81030
Synonym: TβMCA
Target: FXR
Stephacidin B
T37452
Synonym:
Target:
Isojacareubin
TN4300
Synonym:
Target: MAPK, PKC, Antifection

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00381 PIGR Protein, Human, Recombinant (hFc) Human Human Cells
PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates ...
TMPJ-00345 IGF2BP-2 Protein, Human, Recombinant (His) Human E. coli
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to...
TMPY-01283 Glypican 3/GPC3 Protein, Human, Recombinant (His) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-00502 Glypican 3/GPC3 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-00545 Dermcidin Protein, Human, Recombinant (hFc) Human HEK293
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely dia...
TMPY-02292 IGSF11 Protein, Human, Recombinant (His) Human HEK293
Immunoglobulin superfamily member 11(IGSF11) is expressed on the plasma membrane in the testis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins sh...
TMPY-02509 Alpha-fetoprotein Protein, Human, Recombinant (His) Human HEK293
Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moie...
TMPY-01139 PDGFRA Protein, Human, Recombinant (His) Human HEK293
PDGFRA, also known as CD140a, together with the structurally homolog protein PDGFRB (CD140b), are cell surface receptors for members of the platelet-derived growth factor family. They are members of the class III subfami...
TMPY-00991 LIFR Protein, Human, Recombinant (His) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-05493 LIFR Protein, Human, Recombinant (hFc) Human HEK293
LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-00915 Serpin A1 Protein, Human, Recombinant (His) Human HEK293
SerpinA1, also known as Alpha-1 antitrypsin (AAT), is a prototype member of the Serpin superfamily of the serine protease inhibitors. This serine protease inhibitor blocks the protease, neutrophil elastase. Alpha-1 antit...
TMPY-03111 PIK3IP1 Protein, Human, Recombinant (hFc) Human HEK293
PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, me...
TMPY-04933 PIK3IP1 Protein, Mouse, Recombinant (His) Mouse HEK293
PIK3IP1 contains 1 kringle domain and is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepatocellular carcinoma. PI3K is a well-known regulator of cell division, motility, me...
TMPK-01197 IL-20 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-00051 IL-20 Protein, Human, Recombinant (hFc) Human HEK293
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-00052 IL-20 Protein, Human, Recombinant (His) Human HEK293
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-01198 IL-20 Protein, Mouse, Recombinant (His) Mouse HEK293
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPY-03127 BAMBI Protein, Mouse, Recombinant (hFc) Mouse HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu...
TMPY-01456 BAMBI Protein, Human, Recombinant (His) Human HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu...
TMPY-04334 BAMBI Protein, Mouse, Recombinant (His) Mouse HEK293
BMP and activin membrane-bound inhibitor (BAMBI) is a transmembrane glycoprotein that is a pseudoreceptor of type 1 receptors. BAMBI structurally lacks intracellular serine/ threonine kinase domain but with an extracellu...
TMPK-01268 Complement C2 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to health...
TMPJ-00703 Gankyrin Protein, Human, Recombinant Human E. coli
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblast...
TMPY-02796 KIAA0101 Protein, Human, Recombinant (His) Human E. coli
KIAA11, also known as p15(PAF), is a proliferating cell nuclear antigen-associated factor that interacts with proliferating cell nuclear antigen(PCNA). It was initially isolated in a yeast two-hybrid screen for PCNA bind...
TMPJ-01423 GPC3 Protein, Rhesus macaque, Recombinant (His) Rhesus Macaque Human Cells
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms ...
TMPK-01387 EPhA3 Protein, Canine, Recombinant (His) Canine HEK293
Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude...
TMPJ-00337 GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Glypican-3/GPC3 is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. It is a heparan sulfate proteoglycan, which is overexpressed in various neoplasms ...
TMPY-02757 TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc) Human HEK293
Fn14 (tumor necrosis factor receptor superfamily, member 12A), also known as TNFRSF12A, is the receptor for TNFSF12/TWEAK. Fn14 shares 82% amino acid identity with the mouse sequence. It contains a signal peptide, an ext...
TMPK-01327 EPhA10 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in ...
TMPK-00999 EPhA10 Protein, Human, Recombinant (His) Human HEK293
EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in ...
TMPK-01084 EPhA10 Protein, Mouse, Recombinant (His) Mouse HEK293
EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in ...
TMPY-05805 Glypican 3/GPC3 Protein, Human, Recombinant (S495A, hFc) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-05806 Glypican 3/GPC3 Protein, Human, Recombinant (S495A, mFc) Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-05106 Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-06820 Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-06877 Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPY-06751 Glypican 3/GPC3 Protein, Canine, Recombinant (His) Canine HEK293
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed in the lung, liver, and kidney. It is a heparan sulfate pr...
TMPJ-01271 PIK3IP1 Protein, Human, Recombinant (His) Human Human Cells
Phosphoinositide-3-kinase-interacting protein 1(PIK3IP1) is an enzyme that in humans is encoded by the PIK3IP1 gene.It is a negative regulator of phosphatidylinositol-3-kinase (PI3K), suppresses the development of hepato...
TMPY-04398 MST1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The t...
TMPJ-00700 GADD45B Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPJ-00711 GADD45G Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 Υ (GADD45G) is a nuclear protein which belongs to the GADD45 family. GADD45G is highly expressed in placenta. GADD45G interacts with various proteins whose transcript...
TMPJ-00198 FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-term...
TMPJ-00197 FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human Human Cells
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-term...
TMPJ-00195 FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated Cynomolgus Human Cells
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-term...
TMPY-01579 GBA3 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glyc...
TMPY-06798 Claudin-9 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Claudin-9 (CLDN9) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and a cytoplasmic C tail. CLDN9 modulates the ion- and charge-specific permeability o...
TMPY-06902 Claudin-9 Protein, Human, Recombinant Human HEK293
Claudin-9 (CLDN9) belongs to the claudins family and is a transmembrane protein found in tight junctions with two extracellular loops and a cytoplasmic C tail. CLDN9 modulates the ion- and charge-specific permeability o...
TMPJ-00505 Serpin A1 Protein, Human, Recombinant (aa 25-418, His) Human Human Cells
Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent,...
TMPY-01576 Artemin Protein, Mouse, Recombinant (hFc) Mouse HEK293
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored...
TMPY-06752 HK2 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Hexokinase 2 (HK2), a rate-limiting enzyme in the first step of the glycolysis pathway, expresses at a high level in cancer cells compared with normal cells. HK2 provides a new target for cancer therapy due to its pivota...
TMPY-06763 HK2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Hexokinase 2 (HK2), a rate-limiting enzyme in the first step of the glycolysis pathway, expresses at a high level in cancer cells compared with normal cells. HK2 provides a new target for cancer therapy due to its pivota...
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PIGR Protein, Human, Recombinant (hFc)
TMPJ-00381
Species: Human
Expression System: Human Cells
IGF2BP-2 Protein, Human, Recombinant (His)
TMPJ-00345
Species: Human
Expression System: E. coli
Glypican 3/GPC3 Protein, Human, Recombinant (His)
TMPY-01283
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Mouse, Recombinant (His)
TMPY-00502
Species: Mouse
Expression System: Baculovirus-Insect Cells
Dermcidin Protein, Human, Recombinant (hFc)
TMPY-00545
Species: Human
Expression System: HEK293
IGSF11 Protein, Human, Recombinant (His)
TMPY-02292
Species: Human
Expression System: HEK293
Alpha-fetoprotein Protein, Human, Recombinant (His)
TMPY-02509
Species: Human
Expression System: HEK293
PDGFRA Protein, Human, Recombinant (His)
TMPY-01139
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (His)
TMPY-00991
Species: Human
Expression System: HEK293
LIFR Protein, Human, Recombinant (hFc)
TMPY-05493
Species: Human
Expression System: HEK293
Serpin A1 Protein, Human, Recombinant (His)
TMPY-00915
Species: Human
Expression System: HEK293
PIK3IP1 Protein, Human, Recombinant (hFc)
TMPY-03111
Species: Human
Expression System: HEK293
PIK3IP1 Protein, Mouse, Recombinant (His)
TMPY-04933
Species: Mouse
Expression System: HEK293
IL-20 Protein, Mouse, Recombinant (hFc)
TMPK-01197
Species: Mouse
Expression System: HEK293
IL-20 Protein, Human, Recombinant (hFc)
TMPK-00051
Species: Human
Expression System: HEK293
IL-20 Protein, Human, Recombinant (His)
TMPK-00052
Species: Human
Expression System: HEK293
IL-20 Protein, Mouse, Recombinant (His)
TMPK-01198
Species: Mouse
Expression System: HEK293
BAMBI Protein, Mouse, Recombinant (hFc)
TMPY-03127
Species: Mouse
Expression System: HEK293
BAMBI Protein, Human, Recombinant (His)
TMPY-01456
Species: Human
Expression System: HEK293
BAMBI Protein, Mouse, Recombinant (His)
TMPY-04334
Species: Mouse
Expression System: HEK293
Complement C2 Protein, Cynomolgus, Recombinant (His)
TMPK-01268
Species: Cynomolgus
Expression System: HEK293
Gankyrin Protein, Human, Recombinant
TMPJ-00703
Species: Human
Expression System: E. coli
KIAA0101 Protein, Human, Recombinant (His)
TMPY-02796
Species: Human
Expression System: E. coli
GPC3 Protein, Rhesus macaque, Recombinant (His)
TMPJ-01423
Species: Rhesus Macaque
Expression System: Human Cells
EPhA3 Protein, Canine, Recombinant (His)
TMPK-01387
Species: Canine
Expression System: HEK293
GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00337
Species: Human
Expression System: Human Cells
TWEAKR/TNFRSF12A Protein, Human, Recombinant (hFc)
TMPY-02757
Species: Human
Expression System: HEK293
EPhA10 Protein, Cynomolgus, Recombinant (His)
TMPK-01327
Species: Cynomolgus
Expression System: HEK293
EPhA10 Protein, Human, Recombinant (His)
TMPK-00999
Species: Human
Expression System: HEK293
EPhA10 Protein, Mouse, Recombinant (His)
TMPK-01084
Species: Mouse
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (S495A, hFc)
TMPY-05805
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (S495A, mFc)
TMPY-05806
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated
TMPY-05106
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His)
TMPY-06820
Species: Cynomolgus
Expression System: HEK293
Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06877
Species: Human
Expression System: HEK293
Glypican 3/GPC3 Protein, Canine, Recombinant (His)
TMPY-06751
Species: Canine
Expression System: HEK293
PIK3IP1 Protein, Human, Recombinant (His)
TMPJ-01271
Species: Human
Expression System: Human Cells
MST1 Protein, Human, Recombinant (His)
TMPY-04398
Species: Human
Expression System: Baculovirus-Insect Cells
GADD45B Protein, Human, Recombinant (His)
TMPJ-00700
Species: Human
Expression System: E. coli
GADD45G Protein, Human, Recombinant (His)
TMPJ-00711
Species: Human
Expression System: E. coli
FGL1 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00198
Species: Human
Expression System: Human Cells
FGL1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPJ-00197
Species: Human
Expression System: Human Cells
FGL1 Protein, Cynomolgus, Recombinant (Avi & His), Biotinylated
TMPJ-00195
Species: Cynomolgus
Expression System: Human Cells
GBA3 Protein, Human, Recombinant (His)
TMPY-01579
Species: Human
Expression System: Baculovirus-Insect Cells
Claudin-9 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06798
Species: Human
Expression System: HEK293
Claudin-9 Protein, Human, Recombinant
TMPY-06902
Species: Human
Expression System: HEK293
Serpin A1 Protein, Human, Recombinant (aa 25-418, His)
TMPJ-00505
Species: Human
Expression System: Human Cells
Artemin Protein, Mouse, Recombinant (hFc)
TMPY-01576
Species: Mouse
Expression System: HEK293
HK2 Protein, Mouse, Recombinant (His)
TMPY-06752
Species: Mouse
Expression System: Baculovirus-Insect Cells
HK2 Protein, Human, Recombinant (His)
TMPY-06763
Species: Human
Expression System: Baculovirus-Insect Cells
Cat No. Product Name
L5510 Drug-induced Liver Injury (DILI) Compound Library

1040 compounds
A unique collection of 1040 hepatotoxicity causing compounds, a powerful tool for drug toxicity study, can be used for HTS and HCS screening;
TargetMol