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IL-20 Protein, Mouse, Recombinant (His)

IL-20 Protein, Mouse, Recombinant (His)
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IL-20 Protein, Mouse, Recombinant (His)

Catalog No. TMPK-01198
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 19.5 kDa and the accession number is Q9JKV9.
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Pack SizePriceAvailabilityQuantity
100 μg$418In Stock
500 μg$1,6707-10 days
1 mg$2,8007-10 days
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Biological Description

Biological Information
Mouse IL-20RA, hFc Tag captured on CM5 Chip via Protein A can bind Mouse IL-20, His Tag with an affinity constant of 14.26 μM as determined in SPR assay.
Description
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 19.5 kDa and the accession number is Q9JKV9.
Species
Mouse
Expression System
HEK293 Cells
TagN-His
Accession NumberQ9JKV9
Synonyms
Cytokine Zcyto10,IL-20,IL10D,Zcyto10,MGC96907
Construction
Leu25- Leu176
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight19.5 kDa (predicted). Due to glycosylation, the protein migrates to 20-22 kDa based on Tris-Bis PAGE result.
Endotoxin< 1 EU/μg by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl (pH 8.0).
Stability & Storage
It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC.

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