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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $418 | In Stock | |
500 μg | $1,670 | 7-10 days | |
1 mg | $2,800 | 7-10 days |
Biological Information | Mouse IL-20RA, hFc Tag captured on CM5 Chip via Protein A can bind Mouse IL-20, His Tag with an affinity constant of 14.26 μM as determined in SPR assay. |
Description | Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. IL-20 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 19.5 kDa and the accession number is Q9JKV9. |
Species | Mouse |
Expression System | HEK293 Cells |
Tag | N-His |
Accession Number | Q9JKV9 |
Synonyms | Cytokine Zcyto10,IL-20,IL10D,Zcyto10,MGC96907 |
Construction | Leu25- Leu176 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | 19.5 kDa (predicted). Due to glycosylation, the protein migrates to 20-22 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl (pH 8.0). |
Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progression has not yet been investigated. In addition, IL-20 expression was significantly associated with tumor size, metastasis, TNM stage and poor prognosis in patients with HCC. |
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