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Antitumor agent-92
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Catalog No. T74768Cas No. 2922842-01-9
Antitumor Agent-92, an Icaritin derivative, induces G0/G1 phase cell cycle arrest and promotes apoptosis. This compound shows promise for hepatocellular carcinoma (HCC) research [1].
Antitumor agent-92
Antitumor agent-92
😃Good
Catalog No. T74768Cas No. 2922842-01-9
Antitumor Agent-92, an Icaritin derivative, induces G0/G1 phase cell cycle arrest and promotes apoptosis. This compound shows promise for hepatocellular carcinoma (HCC) research [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | 8-10 weeks | |
| 50 mg | Inquiry | 8-10 weeks |
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Product Introduction
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Chemical Properties
| Description | Antitumor Agent-92, an Icaritin derivative, induces G0/G1 phase cell cycle arrest and promotes apoptosis. This compound shows promise for hepatocellular carcinoma (HCC) research [1]. |
| In vitro | Antitumor agent-92 (Compound 11c; 2-8 μM; 48 hours) induces apoptosis in HepG2 and SMMC-7721 cells, with increased effects at higher concentrations [1]. The compound also promotes G0/G1 phase arrest in these cells [1]. Additionally, Antitumor agent-92 upregulates P21 and downregulates Cdc2 p34 and CDK4 [1]. |
| Molecular Weight | 611.68 |
| Formula | C33H41NO10 |
| Cas No. | 2922842-01-9 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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