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DMBA

🥰Excellent
Catalog No. T36696Cas No. 57-97-6
Alias 7,12-DMBA, 7,12-Dimethylbenzanthracene, 7,12-Dimethylbenz[a]anthracene

DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice.

DMBA

DMBA

🥰Excellent
Purity: 99.7%
Catalog No. T36696Alias 7,12-DMBA, 7,12-Dimethylbenzanthracene, 7,12-Dimethylbenz[a]anthraceneCas No. 57-97-6
DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice.
Pack SizePriceAvailabilityQuantity
25 mg$30In Stock
50 mg$40In Stock
100 mg$64In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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Purity:99.7%
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Product Introduction

Bioactivity
Description
DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice.
In vivo
DMBA (0-150 mg/kg, oral administration) induces a decrease in spleen weight and a reduction in the total number of lymphocytes recovered from the spleen in C57BL/6 mice. This model can be used to establish induced cancer models such as skin carcinogenesis, breast cancer, and lung cancer[5].
Alias7,12-DMBA, 7,12-Dimethylbenzanthracene, 7,12-Dimethylbenz[a]anthracene
Chemical Properties
Molecular Weight256.34
FormulaC20H16
Cas No.57-97-6
SmilesCc1c2ccccc2c(C)c2c1ccc1ccccc21
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 2 mg/mL (7.80 mM), Sonication and heating are recommended.
DMSO: 15 mg/mL (58.5 mM), Sonification is recommended.
Acetone: 15 mg/mL (58.5 mM), Sonification is recommended.
DMF: 20 mg/mL
Solution Preparation Table
Ethanol/DMSO/Acetone
1mg5mg10mg50mg
1 mM3.9011 mL19.5053 mL39.0107 mL195.0534 mL
5 mM0.7802 mL3.9011 mL7.8021 mL39.0107 mL
DMSO/Acetone
1mg5mg10mg50mg
10 mM0.3901 mL1.9505 mL3.9011 mL19.5053 mL
20 mM0.1951 mL0.9753 mL1.9505 mL9.7527 mL
50 mM0.0780 mL0.3901 mL0.7802 mL3.9011 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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