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DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $30 | In Stock | |
50 mg | $40 | In Stock | |
100 mg | $64 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice. |
In vivo | DMBA (0-150 mg/kg, oral administration) induces a decrease in spleen weight and a reduction in the total number of lymphocytes recovered from the spleen in C57BL/6 mice. This model can be used to establish induced cancer models such as skin carcinogenesis, breast cancer, and lung cancer[5]. |
Alias | 7,12-DMBA, 7,12-Dimethylbenzanthracene, 7,12-Dimethylbenz[a]anthracene |
Molecular Weight | 256.34 |
Formula | C20H16 |
Cas No. | 57-97-6 |
Smiles | Cc1c2ccccc2c(C)c2c1ccc1ccccc21 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | Ethanol: 2 mg/mL (7.80 mM), Sonication and heating are recommended. DMSO: 15 mg/mL (58.5 mM), Sonification is recommended. Acetone: 15 mg/mL (58.5 mM), Sonification is recommended. DMF: 20 mg/mL | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO/Acetone
DMSO/Acetone
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