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HSP90-IN-21

Catalog No. T86691Cas No. 2521791-38-6

HSP90-IN-21 (5e) serves as an antiplasmodial agent, exhibiting IC 50 values of 0.04, 0.17, and 2.91 μM against the erythrocytic stages of P. falciparum strains (Pf3D7 and PfDd2) and cytotoxicity against the human liver hepatocellular carcinoma cell line (HepG2), respectively [1].

HSP90-IN-21

HSP90-IN-21

Catalog No. T86691Cas No. 2521791-38-6
HSP90-IN-21 (5e) serves as an antiplasmodial agent, exhibiting IC 50 values of 0.04, 0.17, and 2.91 μM against the erythrocytic stages of P. falciparum strains (Pf3D7 and PfDd2) and cytotoxicity against the human liver hepatocellular carcinoma cell line (HepG2), respectively [1].
Pack SizePriceAvailabilityQuantity
10 mgInquiry10-14 weeks
50 mgInquiry10-14 weeks
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Product Introduction

Bioactivity
Description
HSP90-IN-21 (5e) serves as an antiplasmodial agent, exhibiting IC 50 values of 0.04, 0.17, and 2.91 μM against the erythrocytic stages of P. falciparum strains (Pf3D7 and PfDd2) and cytotoxicity against the human liver hepatocellular carcinoma cell line (HepG2), respectively [1].
Chemical Properties
Molecular Weight419.9
FormulaC24H22ClN3O2
Cas No.2521791-38-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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