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Thymectacin
🥰Excellent
Catalog No. T24881Cas No. 232925-18-7
Alias NB-1011, NB1011, NB 1011
Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.
Thymectacin
🥰Excellent
Purity: 99.82%
Catalog No. T24881Alias NB-1011, NB1011, NB 1011Cas No. 232925-18-7
Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $118 | In Stock | |
| 5 mg | $293 | In Stock | |
| 10 mg | $475 | In Stock | |
| 25 mg | $953 | In Stock | |
| 50 mg | $1,530 | In Stock | |
| 100 mg | $1,980 | In Stock |
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Purity:99.82%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors. |
| Targets&IC50 | MDA-MB-231 cells:79 μM (EC50), PC3 cells:155 μM (EC50), HT 115 cells:245 μM (EC50) |
| In vitro | The main clinical candidate, Thymectacin, showed only moderate activity in vitro, with EC50 values ranging from 79-245 μM in our assay. However, relatively minor structural adjustments resulted in a significant increase in potency.MDA-MB 231 EC50=79 μM, HT 115 EC50=245 μM, and PC-3 EC50=155 μM. [1] |
| Alias | NB-1011, NB1011, NB 1011 |
| Molecular Weight | 574.32 |
| Formula | C21H25BrN3O9P |
| Cas No. | 232925-18-7 |
| Smiles | O=C1N(C=C(/C=C/Br)C(=O)N1)[C@@H]2O[C@H](COP(OC3=CC=CC=C3)(N[C@H](C(OC)=O)C)=O)[C@@H](O)C2 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL(139.30 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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