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Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $43 | In Stock | |
100 mg | $57 | In Stock | |
500 mg | $138 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | (-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells. |
In vivo | Epigallocatechol Gallate (5 and 20 mg/kg, p.o.) inhibits the growth of tumor in the subcutaneous orthotopic transplant model[4]. |
Cell Research | LoVo, SW480, HCT-8, and HT-29 cells are seeded in 96-well plates at a concentration of 5×103?cells; each cell line is totally seeded in the 12 wells. Complete medium is added to the wells, up to 200 μL; the medium contains 0 μg/mL, 10 μg/mL, 20 μg/mL, and 35 μg/mL of epigallocatechol gallate. The inhibition rate=[1 - (absorbance of Epigallocatechol Gallate group - absorbance of control group)/(absorbance of control group - absorbance of blank control group)] × 100. |
Alias | Epigallocatechol Gallate, EGCG |
Molecular Weight | 458.37 |
Formula | C22H18O11 |
Cas No. | 989-51-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 100 mg/mL (218.16 mM) ![]() H2O: 50 mg/mL (109.08 mM), Sonication is recommended. ![]() Ethanol: 45.8 mg/mL (100 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/H2O/DMSO
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