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Beta-mangostin

Beta-mangostin
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Purity:99.69%
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Beta-mangostin

Catalog No. TN1019Cas No. 20931-37-7
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. Beta-mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
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Pack SizePriceAvailabilityQuantity
1 mg$78In Stock
5 mg$185In Stock
10 mg$273In Stock
25 mg$459In Stock
50 mg$673In Stock
1 mL x 10 mM (in DMSO)$212In Stock
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Product Introduction

Bioactivity
Description
Beta-mangostin (β-Mangostin) is a xanthone compound with antibacterial and antimalarial activities. Beta-mangostin present in Cratoxylum arborescens and exhibits antimycobacterial activity against Mycobacterium tuberculosis with an MIC of 6.25 μg/mL. Beta-mangostin possesses in vitro antimalarial activity against Plasmodium falciparum, with an IC50 of 3.00 μg/mL. Beta-mangostin has potent anticancer activity against various cancers (such as hepatocellular carcinoma, leukaemic).
In vitro
Beta-Mangostin induces the intrinsic apoptosis pathway in HL60 cells by generating reactive oxygen species and suppressing the HSP70 gene, coupled with a G0/G1 cell-cycle arrest[2].
Aliasβ-Mangostin
Chemical Properties
Molecular Weight424.49
FormulaC25H28O6
Cas No.20931-37-7
Storage & Solubility Information
Storagekeep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 24 mg/mL (56.53 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3558 mL11.7788 mL23.5577 mL117.7884 mL
5 mM0.4712 mL2.3558 mL4.7115 mL23.5577 mL
10 mM0.2356 mL1.1779 mL2.3558 mL11.7788 mL
20 mM0.1178 mL0.5889 mL1.1779 mL5.8894 mL
50 mM0.0471 mL0.2356 mL0.4712 mL2.3558 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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