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Shogaol

🥰Excellent
Catalog No. T6S1699Cas No. 555-66-8
Alias 6-Shogaol, [6]-Shogaol

1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.

Shogaol

Shogaol

🥰Excellent
Purity: 99.39%
Catalog No. T6S1699Alias 6-Shogaol, [6]-ShogaolCas No. 555-66-8
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.
Pack SizePriceAvailabilityQuantity
2 mg$36In Stock
5 mg$56In Stock
10 mg$93In Stock
25 mg$189In Stock
50 mg$297In Stock
100 mg$455In Stock
500 mg$987In Stock
1 mL x 10 mM (in DMSO)$62In Stock
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Purity:99.39%
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Product Introduction

Bioactivity
Description
1. 6-Shogaol (6-Shogaol) has antipyretic and analgesic effects in addition to inhibitory effect on lipoxygenase activity. 2. 6-shogaol has anti-inflammatory property, reduces the inflammatory response and protected the femoral cartilage from damage produced in a CFA monoarthritic model of the knee joint of rats. 3. 6-Shogaol inhibits the growth of human cancer cells and induces apoptosis in COLO 25 cells through modulation of mitochondrial functions regulated by reactive oxygen species (ROS). 4. 6-Shogaol effectively inhibit invasion and metastasis of hepatocellular carcinoma through diverse molecular mechanisms, including inhibition of the MAPK and PI3k/Akt pathways and NF-κB and STAT3 activities to suppress expression of MMP-2/-9 and uPA and block angiogenesis, could further regulate urokinase-type plasminogen activity.
Alias6-Shogaol, [6]-Shogaol
Chemical Properties
Molecular Weight276.37
FormulaC17H24O3
Cas No.555-66-8
SmilesCCCCC\C=C\C(=O)CCc1ccc(O)c(OC)c1
Relative Density.1.033 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (199.01 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6183 mL18.0917 mL36.1834 mL180.9169 mL
5 mM0.7237 mL3.6183 mL7.2367 mL36.1834 mL
10 mM0.3618 mL1.8092 mL3.6183 mL18.0917 mL
20 mM0.1809 mL0.9046 mL1.8092 mL9.0458 mL
50 mM0.0724 mL0.3618 mL0.7237 mL3.6183 mL
100 mM0.0362 mL0.1809 mL0.3618 mL1.8092 mL

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