Popular product application

Organoids are three-dimensional miniature tissue structures cultured in a laboratory environment, capable of mimicking the cellular composition, structure, and function of real organs, and have become an important tool in modern biomedical research. They play a key role in constructing disease models, drug screening, and toxicity testing. Organoids typically originate from stem cells, which can differentiate into various cell types under specific culture conditions, eventually forming organoids. As the core of this process, stem cells have remarkable self-renewal capabilities and the potential to differentiate into various cell types.

To effectively promote the differentiation of stem cells and the formation of organoids, scientists use specific compounds that play vital roles in cell proliferation, differentiation, and survival. These include Epidermal Growth Factor (EGF), Fibroblast Growth Factor (FGF), and Transforming Growth Factor beta (TGF-β). Additionally, compounds like GSK-3β inhibitors (e.g., CHIR99021), PI3K inhibitors (e.g., LY294002), and Smoothened agonists (e.g., SAG) can be used to regulate specific signaling pathways, thereby influencing the fate of stem cells.In the field of organoid and stem cell research, our company can provide a variety of inhibitors and activators, r ecombinant proteins, and specialized compound libraries. These include stem cell differentiation compound library, cell cycle compound library, Wnt/Hedgehog/Notch pathway compound library, and MAPK inhibitor library. These resources assist researchers in conducting studies on stem cell-induced differentiation, organoid culture, and drug screening.