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Infectious diseases are illnesses caused by various pathogens such as bacteria, viruses, fungi, or parasites, and they can be transmitted through various means including air, food, water, or direct human contact. Common infectious diseases include influenza, HIV/AIDS, tuberculosis, malaria, and novel coronavirus diseases. These diseases pose a serious threat to global public health.
In the prevention and treatment of infectious diseases, the development of vaccines and the use of effective antibiotics and antiviral drugs play a crucial role. To address the increasing challenge of antibiotic resistance and emerging infectious diseases, the development of novel small molecule drugs is a key strategy in overcoming these global health threats.In the field of infectious diseases, our company possesses a variety of inhibitors and activators targeting key objectives in the area of infectious diseases. We also offer several specialized compound libraries, such as anti-infection compound library, anti-viral compound library, anti-bacterial compound library, and anti-parasitic natural product library. These resources help researchers rapidly and effectively identify potential anti-infective compounds, thereby accelerating the discovery and development process of infectious disease drugs.
Popular targets recommendations
Reverse Transcriptase
A reverse transcriptase (RT) is an enzyme used to generate complementary DNA (cDNA) from an RNA template, a process termed reverse transcription. Reverse transcriptases are used by retroviruses to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes, and by some non-retroviruses such as the hepatitis B virus, a member of the Hepadnaviridae, which are dsDNA-RT viruses.
50 Products
HCV Protease
NS2-3 protease (of hepatitis C virus, HCV) is an enzyme responsible for proteolytic cleavage between NS2 and NS3, which are non-structural proteins that form part of the HCV virus particle. NS3 protease of hepatitis C virus, on the other hand, is responsible for the cleavage of non-structural protein downstream. Both of these proteases are directly involved in HCV genome replication, that is, during the viral life-cycle that leads to virus multiplication in the host that has been infected by the virus.
130 Products
HIV ProteaseR
HIV-1 protease (PR) is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins (namely, Gag and Gag-Pol[3]) at nine cleavage sites to create the mature protein components of an HIV virion, the infectious form of a virus outside of the host cell. Without effective HIV protease, HIV virions remain uninfectious.
323 Products
SARS CoV
Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1) is a strain of virus that causes severe acute respiratory syndrome (SARS). It is an enveloped, positive-sense, single-stranded RNA virus which infects the epithelial cells within the lungs. The virus enters the host cell by binding to the ACE2 receptor. It infects humans, bats, and palm civets.
175 Products
RSV
Human orthopneumovirus (also known as human respiratory syncytial virus, or HRSV, or just RSV) is a syncytial virus that causes respiratory tract infections.
25 Products
HSV
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known by their taxonomical names Human alphaherpesvirus 1 and Human alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of new viruses that produce viral infections in the majority of humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are common and contagious. They can be spread when an infected person begins shedding the virus.
89 Products
HBV
Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver. It can cause both acute and chronic infection. Many people have no symptoms during the initial infection.Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver. It can cause both acute and chronic infection. Many people have no symptoms during the initial infection.
97 Products
Influenza Virus
Influenza, commonly known as 'the flu', is an infectious disease caused by an influenza virus. Symptoms can be mild to severe. The most common symptoms include: high fever, runny nose, sore throat, muscle and joint pain, headache, coughing, and feeling tired . Three of the four types of influenza viruses affect humans: Type A, Type B, and Type C. Type D has not been known to infect humans, but is believed to have the potential to do so.
180 Products
Parasite
Parasites include protozoans such as the agents of malaria, sleeping sickness, and amoebic dysentery; animals such as hookworms, lice, mosquitoes, and vampire bats; fungi such as honey fungus and the agents of ringworm; and plants such as mistletoe, dodder, and the broomrapes. There are six major parasitic strategies of exploitation of animal hosts, namely parasitic castration, directly transmitted parasitism (by contact), trophically transmitted parasitism (by being eaten), vector-transmitted parasitism, parasitoidism, and micropredation.
382 Products
Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria and is the most important type of antibacterial agent for fighting bacterial infections. Antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity.
685 Products
Antifungal
An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others.
369 Products
Antibacterial
Antibacterial usually refers to an antibiotic, a principal type of antimicrobial agent used mainly against bacteria; it may kill or inhibit them.
1097 Products
Popular compound libraries recommendations
Anti-Infection Compound Library
Listed in literature
L18002977 Compounds
A unique collection of 2977 anti-infective compounds including anti-bacterial, anti-fungi, anti-Human Cytomegalovirus (HCMV), anti-HIV, anti-SARS, anti-influenza, etc;
Listed in literatureAnti-Viral Compound Library Listed in literature
L17001040 Compounds
A unique collection of 1040 anti-virus compounds effective for new anti-virus drugs high throughput screening and high content screening;
Listed in literatureAnti-Fungal Compound Library Listed in literature
L4500253 Compounds
A unique collection of 253 antifungal compounds effective for drug repurposing screening, combination screening and biological investigation.
Listed in literatureAnti-COVID-19 Traditional Chinese Medicine Compound Library Listed in literature
L67201162 Compounds
A unique collection of 1162 monomers from 60 TCM plants, a powerful tool for anti-COVID-19 drug discovery, can be used for HTS and HCS screening；
Listed in literatureAntiparasitic Natural Product Library Listed in literature
L6620253 Compounds
A unique collection of 253 natural products with antiparasitic activity, a powerful tool for high throughput screening (HTS) and high content screening (HCS);
Listed in literatureAnti-Bacterial Compound Library Listed in literature
L4520921 Compounds
A unique collection of 921 antibacterial bioactive compounds, a powerful tool for antibacterial drug development;
Listed in literature- TOP
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