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Plecanatide
🥰Excellent
Catalog No. T9080Cas No. 467426-54-6
Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.
Plecanatide
🥰Excellent
Purity: 97.51%
Catalog No. T9080Cas No. 467426-54-6
Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $72 | In Stock | |
| 5 mg | $189 | In Stock | |
| 10 mg | $313 | In Stock | |
| 25 mg | $622 | In Stock | |
| 50 mg | $879 | In Stock | |
| 100 mg | $1,180 | In Stock |
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Purity:97.51%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Plecanatide acetate is an analogue of Uroguanylin. It is an orally active guanylate cyclase-C (GC-C) receptor agonist. |
| Targets&IC50 | GC-C:190 nM (EC50) |
| In vitro | Plecanatide (1 nM-10 μM) activates the GC-C receptor to stimulate cyclic guanosine monophosphate (cGMP) synthesis in T84 cells in a dose-dependent manner, with an EC50 of 190 nM[2]. |
| Molecular Weight | 1681.89 |
| Formula | C65H104N18O26S4 |
| Cas No. | 467426-54-6 |
| Smiles | N(C([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]2(C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@](CSSC1)(C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC(=O)N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CSSC2)[H])[H])[H] |
| Relative Density. | 1.47 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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