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Sinitrodil

Catalog No. T34648Cas No. 143248-63-9
Alias ITF-296, ITF296, ITF 296

Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.

Sinitrodil

Sinitrodil

Purity: 99%
Catalog No. T34648Alias ITF-296, ITF296, ITF 296Cas No. 143248-63-9
Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
Pack SizePriceAvailabilityQuantity
1 mg$142In Stock
5 mg$350In Stock
10 mg$530In Stock
25 mg$859In Stock
50 mg$1,180In Stock
100 mg$1,590In Stock
500 mg$3,190In Stock
1 mL x 10 mM (in DMSO)$423In Stock
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Purity:99%
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Product Introduction

Bioactivity
Description
Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
In vivo
Sinitrodil (10、20、40 mg; oral) increased gradually brachial artery compliance with increasing doses of sinitrodil (by 10, 20, and 27% with 10, 20, and 40 mg sinitrodil, respectively). Total peripheral resistance index decreased with isosorbide dinitrate (by 11%) and 40 mg sinitrodil (by 7%), while it remained unchanged with 10 mg and 20 mg sinitrodil.[3]
AliasITF-296, ITF296, ITF 296
Chemical Properties
Molecular Weight238.2
FormulaC10H10N2O5
Cas No.143248-63-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 27.5 mg/mL (58.27 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.1982 mL20.9908 mL41.9815 mL209.9076 mL
5 mM0.8396 mL4.1982 mL8.3963 mL41.9815 mL
10 mM0.4198 mL2.0991 mL4.1982 mL20.9908 mL
20 mM0.2099 mL1.0495 mL2.0991 mL10.4954 mL
50 mM0.0840 mL0.4198 mL0.8396 mL4.1982 mL

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