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Nitroprusside disodium dihydrate

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Catalog No. T6991Cas No. 13755-38-9
Alias Sodium Nitroprusside Dihydrate, Sodium Nitroferricyanide(III) Dihydrate

Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.

Nitroprusside disodium dihydrate

Nitroprusside disodium dihydrate

🥰Excellent
Catalog No. T6991Alias Sodium Nitroprusside Dihydrate, Sodium Nitroferricyanide(III) DihydrateCas No. 13755-38-9
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
Pack SizePriceAvailabilityQuantity
500 mg42 €In Stock
1 mL x 10 mM (in DMSO)45 €In Stock
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Product Introduction

Bioactivity
Description
Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.
In vitro
Sodium Nitroprusside is a potent vasodilator. Sodium nitroprusside has potent vasodilating effects in arterioles and venules. Sodium Nitroprusside breaks down in circulation to release nitric oxide (NO). NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. The end result is vascular smooth muscle relaxation, which allow vessels to dilate. [1] Sodium nitroprusside decreases the proliferation of vascular smooth muscle cells. [2]
In vivo
Sodium nitroprusside (5 mg/kg) significantly reduces the intestinal ischemiareperfusion injury as a nitric oxide donor in rats. [3]
AliasSodium Nitroprusside Dihydrate, Sodium Nitroferricyanide(III) Dihydrate
Chemical Properties
Molecular Weight297.95
FormulaC5H4FeN6Na2O3
Cas No.13755-38-9
SmilesO.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
Relative Density.1.72
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 20 mg/mL (67.13 mM), Sonication is recommended.
H2O: 55 mg/mL (184.6 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
Solution Preparation Table
DMSO/H2O
1mg5mg10mg50mg
1 mM3.3563 mL16.7813 mL33.5627 mL167.8134 mL
5 mM0.6713 mL3.3563 mL6.7125 mL33.5627 mL
10 mM0.3356 mL1.6781 mL3.3563 mL16.7813 mL
20 mM0.1678 mL0.8391 mL1.6781 mL8.3907 mL
50 mM0.0671 mL0.3356 mL0.6713 mL3.3563 mL
H2O
1mg5mg10mg50mg
100 mM0.0336 mL0.1678 mL0.3356 mL1.6781 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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