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Sodium Nitroprusside

Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.

Catalog No. T0003Cas No. 14402-89-2

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Sodium Nitroprusside

Catalog No. T0003Cas No. 14402-89-2

Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
50 mg	$40	In Stock
100 mg	$50	In Stock
200 mg	$67	In Stock
500 mg	$87	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Related Compound Libraries of "Sodium Nitroprusside"

Product Introduction

Bioactivity

Description	Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.
In vitro	Administering 5 mg/kg of sodium nitroprusside, acting as a nitric oxide donor, effectively mitigates intestinal ischemia-reperfusion injury in rats.
In vivo	Sodium nitroprusside inhibits the proliferation of vascular smooth muscle. As an effective vasodilator, it exhibits pronounced dilation effects particularly in the arterioles and venules. During circulation, sodium nitroprusside decomposes to release nitric oxide (NO), which activates guanylate cyclase in vascular smooth muscle and augments intracellular cyclic guanosine monophosphate (cGMP) production, promoting the relaxation of the smooth muscle and consequent vasodilation.
Alias	Sodium Nitroferricyanide, Nitroprusside Sodium, Ro 21-2498

Chemical Properties

Molecular Weight	261.92
Formula	Na₂Fe(CN)5NO
Cas No.	14402-89-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 55 mg/mL (209.99 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8180 mL	19.0898 mL	38.1796 mL	190.8980 mL
5 mM	0.7636 mL	3.8180 mL	7.6359 mL	38.1796 mL
10 mM	0.3818 mL	1.9090 mL	3.8180 mL	19.0898 mL
20 mM	0.1909 mL	0.9545 mL	1.9090 mL	9.5449 mL
50 mM	0.0764 mL	0.3818 mL	0.7636 mL	3.8180 mL
100 mM	0.0382 mL	0.1909 mL	0.3818 mL	1.9090 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Keywords

InhibitorinhibitSodium Nitroprusside