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Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 mg | $40 | In Stock | |
100 mg | $50 | In Stock | |
200 mg | $67 | In Stock | |
500 mg | $87 | In Stock | |
1 mL x 10 mM (in DMSO) | $50 | In Stock |
Description | Sodium Nitroprusside (Ro 21-2498) is a potent vasodilator, releasing in blood with no spontaneously. |
In vitro | Administering 5 mg/kg of sodium nitroprusside, acting as a nitric oxide donor, effectively mitigates intestinal ischemia-reperfusion injury in rats. |
In vivo | Sodium nitroprusside inhibits the proliferation of vascular smooth muscle. As an effective vasodilator, it exhibits pronounced dilation effects particularly in the arterioles and venules. During circulation, sodium nitroprusside decomposes to release nitric oxide (NO), which activates guanylate cyclase in vascular smooth muscle and augments intracellular cyclic guanosine monophosphate (cGMP) production, promoting the relaxation of the smooth muscle and consequent vasodilation. |
Alias | Sodium Nitroferricyanide, Ro 21-2498, Nitroprusside Sodium |
Molecular Weight | 261.92 |
Formula | Na2Fe(CN)5NO |
Cas No. | 14402-89-2 |
Smiles | [Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N |
Relative Density. | 1.72 g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 55 mg/mL (209.99 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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