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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | α-Conotoxin GID is a paralytic peptide neurotoxin that selectively antagonizes nAChR with IC50 values of 5 nM (α7), 3 nM (α3β2), and 150 nM (α4β2). It is a small, disulfide-rich peptide with the potential for chronic pain inhibition. The presence of a C-terminal carboxylate in α-Conotoxin GID is crucial, as its substitution with a C-terminal carboxamide results in a loss of activity against α4β2 nAChR. This compound is derived from species of the genus Conus [1] [2] [3]. |
Molecular Weight | 2186.39 |
Formula | C84H132N30O31S4 |
Cas No. | 547741-78-6 |
Storage | keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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