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pBD-1
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Catalog No. TP2151Cas No. 206367-33-1
pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites with the contribution of mucosal and systemic host defenses in pigs.
pBD-1
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Catalog No. TP2151Cas No. 206367-33-1
pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites with the contribution of mucosal and systemic host defenses in pigs.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | Inquiry | Backorder | |
| 500 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | pBD-1 is an endogenous and constitutively expressed antimicrobial peptide (AMP) from porcine tissues, particularly expresses in pig mucosal epithelial sites with the contribution of mucosal and systemic host defenses in pigs. |
| Targets&IC50 | Antibacterial: |
| In vitro | In a northern blot analysis, pBD-1 mRNA only expresses in tongue epithelial tissues from 4-5 week-old pigs. In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from the nasal septum to lung) and gastrointestinal (from the esophagus to rectum) tracts. In addition, it is detected in thymus, liver, kidney, urinary bladder, spleen, lymph node, brain, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils, and the umbilical cord. The only cells that do not express pBD-1 are peripheral blood mononuclear cells. |
| Molecular Weight | 7065.98 |
| Formula | C310H543N91O73S11 |
| Cas No. | 206367-33-1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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