Shopping Cart
- Remove All
Your shopping cart is currently empty
GLP-1 (9-36) amide
🥰Excellent
Catalog No. TP2252Cas No. 161748-29-4
GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor. GLP-1 (9-36) amide potently inhibits hepatic glucose production (HGP) and is a weak insulinotropic agent.
GLP-1 (9-36) amide
🥰Excellent
Purity: 97%
Catalog No. TP2252Cas No. 161748-29-4
GLP-1 (9-36) amide is an antagonist at the human GLP-1 receptor. GLP-1 (9-36) amide potently inhibits hepatic glucose production (HGP) and is a weak insulinotropic agent.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $81 | In Stock | |
| 5 mg | $255 | In Stock | |
| 10 mg | $378 | In Stock | |
| 25 mg | $626 | In Stock | |
| 50 mg | $883 | In Stock | |
| 100 mg | $1,190 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "GLP-1 (9-36) amide"
Orforglipron
LY3502970, GLP-1 receptor agonist 1
T114082212020-52-3
Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.
- $256
Size
QTY
NNC 92-1687
NNC92-1687, NNC-92-1687
T2818222903-37-3In house
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
- $397
Size
QTY
6α-Methylprednisolone 21-hemisuccinate sodium salt
Metypresol, Methylprodnisolone Sodium Succinate, Methylprednisolone sodium succinate, Corticel, Asmacortone, 6-Methylprednisolone succinate sodium
T02942375-03-3
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
- $39
Size
QTY
Tirzepatide Acetate(2023788-19-2 free base)
TP1111L
Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels by combining dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.[3]
- $358
Size
QTY
PF-06882961
T124312230198-02-2
PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
- $42
Size
QTY
LSN3318839
LSN-3318839, LSN 3318839
T631662764704-18-7In house
LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can be used to lower blood glucose.
- $213
Size
QTY
(S, R)-LSN 3318839
(S, R)-LSN 3318839(Isomer-2764704-18-7)
T63166L2765539-92-0In house
(S,R)-LSN 3318839 enhances GLP-1R, shows strong blood sugar lowering in animals, works with sitagliptin.
- $195
Size
QTY
PF-06882961 Tris
UNII-2HJV78O0SS
T88762230198-03-3
PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
- $133
Size
QTY
Adomeglivant
LY2409021
T141301488363-78-5
Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.
- $118
Size
QTY
Glucagon (1-29), bovine, human, porcine hydrochloride
Glucagon hydrochloride
T15389L28270-04-4
Glucagon (1-29), bovine, human, porcine hydrochloride (Porcine glucagon hydrochloride) is a peptide hormone produced by pancreatic α-cells that activates HNF4α, increases HNF4α phosphorylation, and stimulates gluconeogenesis.
- $79
Size
QTY
L-168049
L-168,049
T22893191034-25-0
L-168049 is a selective and non-competitive antagonist of human glucagon receptor with IC50s of 3.7 nM, 63 nM, and 60 nM for human, murine, and canine, respectively.
- $48
Size
QTY
HAEGTFT acetate(926018-95-3 free base)
TP1419L
HAEGTFT acetate is the first N-terminal 1-7 residues of GLP-1 peptide.
- $103
Size
QTY
Select Batch
Purity:97%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | antagonist at the human GLP-1 receptor |
| In vivo | After subcutaneous (s.c.) administration of GLP-1 to dogs the plasma immunoreactivity of GLP-1 measured by two different radioimmunoassays (RIAs) were higher than that measured by a sandwich enzyme-linked immunosorbent assay (ELISA). This discrepancy was due to the formation of the metabolites GLP-1-(9-36) amide, GLP-1-(7-35) and GLP-1-(7-34). Receptor binding studies using baby hamster kidney cells expressing the human pancreatic GLP-1 receptor showed that the affinity of GLP-1-(9-36) amide was 0.95% of the affinity of GLP-1-(7-36) amide. Furthermore, GLP-1-(9-36) amide was shown to be an antagonist to adenylyl cyclase activity. GLP-1-(9-36) amide was shown to be present in vivo in amounts up to 10-fold that of GLP-1-(7-36) amide[2]. |
| Molecular Weight | 3089.41 |
| Formula | C140H214N36O43 |
| Cas No. | 161748-29-4 |
| Smiles | CC[C@H](C)[C@@H](C(N[C@@H](C)C(N[C@@H](Cc1c[nH]c2c1cccc2)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](Cc1ccccc1)NC([C@H](CCC(O)=O)NC([C@H](CCCCN)NC([C@H](C)NC([C@H](C)NC([C@H](CCC(N)=O)NC(CNC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](Cc(cc1)ccc1O)NC([C@H](CO)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H]([C@@H](C)O)NC([C@H](Cc1ccccc1)NC([C@H]([C@@H](C)O)NC(CNC([C@H](CCC(O)=O)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
| Relative Density. | 1.46 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 0.025% acetic acid: 2 mg/ml |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy GLP-1 (9-36) amide | purchase GLP-1 (9-36) amide | GLP-1 (9-36) amide cost | order GLP-1 (9-36) amide | GLP-1 (9-36) amide chemical structure | GLP-1 (9-36) amide in vivo | GLP-1 (9-36) amide formula | GLP-1 (9-36) amide molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.