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Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $117 | In Stock | |
2 mg | $165 | In Stock | |
5 mg | $262 | In Stock | |
10 mg | $388 | In Stock | |
25 mg | $592 | In Stock | |
50 mg | $828 | In Stock | |
100 mg | $1,110 | In Stock | |
200 mg | $1,480 | In Stock | |
1 mL x 10 mM (in DMSO) | $460 | In Stock |
Description | Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle. |
Targets&IC50 | Ang I:5.7 μM(rabbit lung ACE), Hippuryl-L-histidyl-L-leucine:1.7 μM(rabbit lung ACE) |
In vitro | Tuna AI acetate inhibited rabbit lung ACE non-competitively with Ki values of 1.7 and 5.7 microM with substrates, hippuryl-L-histidyl-L-leucine and angiotensin I, respectively. Tuna AI acetate (5.3 microM) also doubled the effect of bradykinin in the contraction of isolated guinea pig ileum[1]. |
Molecular Weight | 1013.1 |
Formula | C46H68N12O14 |
Smiles | CC(O)=O.O=C(O)C[C@@H](C(O)=O)NC(CNC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CCCCN)NC([C@H]([C@@H](C)CC)NC([C@H](CC3=CNC=N3)NC([C@H]([C@H](O)C)NC([C@H]4NCCC4)=O)=O)=O)=O)=O)=O)=O |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 22.5 mg/mL (22.21 mM) | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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