Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

ANP(1-28) Acetate (human, porcine)

🥰Excellent
Catalog No. TP1220LCas No. 1366000-58-9
Alias Carperitide acetate (89213-87-6 Free base), Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate

Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate), a 28-amino acid hormone, is naturally produced and released by the human heart upon cardiac injury or mechanical stretch. This compound effectively inhibits the secretion of endothelin-1 in a dose-dependent manner.

ANP(1-28) Acetate (human, porcine)

ANP(1-28) Acetate (human, porcine)

🥰Excellent
Purity: 98.24%
Catalog No. TP1220LAlias Carperitide acetate (89213-87-6 Free base), Atrial Natriuretic Peptide (ANP) (1-28), human, porcine AcetateCas No. 1366000-58-9
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate), a 28-amino acid hormone, is naturally produced and released by the human heart upon cardiac injury or mechanical stretch. This compound effectively inhibits the secretion of endothelin-1 in a dose-dependent manner.
Pack SizePriceAvailabilityQuantity
25 mg$57In Stock
Bulk & Custom
Add to Cart
Questions
View More
Select Batch
Purity:98.24%
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Carperitide acetate (Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate), a 28-amino acid hormone, is naturally produced and released by the human heart upon cardiac injury or mechanical stretch. This compound effectively inhibits the secretion of endothelin-1 in a dose-dependent manner.
In vitro
Atrial natriuretic peptide (ANP), isolated from mammalian hearts, exhibits diuretic, natriuretic, and vasodilatory properties. It has been observed that porcine ANP (1-28) not only inhibits the secretion of immunoreactive endothelin-1 in porcine endothelial cells and aorta upon stimulation with Angiotensin II (Ang II) but also elevates cellular cGMP levels. Similarly, human ANP (1-28) suppresses immunoreactive endothelin-1 secretion and enhances cyclic GMP in human umbilical-vein endothelial cells when stimulated by angiotensin II (ANGII) and thrombin. Moreover, in normal rat glomeruli, Human 125I-ANP (1-28) binds to high-affinity receptors, significantly increasing cGMP without affecting cAMP, showcasing its integral role in electrolyte and fluid homeostasis[1,2,3].
AliasCarperitide acetate (89213-87-6 Free base), Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
Chemical Properties
Molecular Weight3140.5
FormulaC129H207N45O41S3
Cas No.1366000-58-9
SmilesC(C)(O)=O.[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(O)=O)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC(=O)[C@@H]3CSSC[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CO)=O)CO)=O)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N3)[H])CC(N)=O)=O)CO)=O
Relative Density.no data available
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 100 mg/mL (31.8 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM0.3184 mL1.5921 mL3.1842 mL15.9210 mL
5 mM0.0637 mL0.3184 mL0.6368 mL3.1842 mL
10 mM0.0318 mL0.1592 mL0.3184 mL1.5921 mL
20 mM0.0159 mL0.0796 mL0.1592 mL0.7961 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy ANP(1-28) Acetate (human, porcine) | purchase ANP(1-28) Acetate (human, porcine) | ANP(1-28) Acetate (human, porcine) cost | order ANP(1-28) Acetate (human, porcine) | ANP(1-28) Acetate (human, porcine) chemical structure | ANP(1-28) Acetate (human, porcine) in vitro | ANP(1-28) Acetate (human, porcine) formula | ANP(1-28) Acetate (human, porcine) molecular weight