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ZINC77292789

🥰Excellent
Catalog No. TP1166Cas No. 116783-35-8
Alias Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH

ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.

ZINC77292789

ZINC77292789

🥰Excellent
Purity: 99.24%
Catalog No. TP1166Alias Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OHCas No. 116783-35-8
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$58In Stock
25 mg$98In Stock
50 mg$170In Stock
100 mg$258In Stock
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Purity:99.24%
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COA HNMR HPLC
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Product Introduction

Bioactivity
Description
ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.
In vitro
The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn antigen)[1].
AliasFmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH
Chemical Properties
Molecular Weight670.66
FormulaC33H38N2O13
Cas No.116783-35-8
SmilesCC(OC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1NC(C)=O)C(NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
Relative Density.1.38 g/cm3
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: soluble

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Keywords

Fmoc-Thr(Ac₃AcNH-a-Gal)-OHZINC 77292789Fmoc-Thr(Ac₃AcNH-alpha-Gal)-OHinhibitInhibitorZINC-77292789ZINC77292789Fmoc-Thr[GalNAc(Ac)3-a-D]-OHFmoc-Thr[GalNAc(Ac)3-alpha-D]-OH
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