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ZINC77292789

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Purity:99.24%

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COA HNMR HPLC

ZINC77292789

Catalog No. TP1166Cas No. 116783-35-8

ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.

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Pack Size	Price	Availability
1 mg	$30	In Stock
2 mg	$39	In Stock
5 mg	$65	In Stock
10 mg	$97	In Stock
25 mg	$163	In Stock
50 mg	$283	In Stock
100 mg	$396	In Stock

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Product Introduction

Bioactivity

Description	ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer which induces the antibody production against tumor cells. ZINC77292789 is a starting material to make trimeric MUC1 immunodominant motif antigen-based anti-cancer vaccine candidates.
In vitro	The Tn antigen is a tumor-associated carbohydrate antigen that is not normally expressed in peripheral tissues or blood cells. Expression of this antigen, which is found in a majority of human carcinomas of all types, arises from a blockage in the normal O-glycosylation pathway in which glycans are extended from the common precursor GalNAcα1-O-Ser/Thr (Tn antigen)[1].
Alias	Fmoc-Thr[GalNAc(Ac)3-α-D]-OH, Fmoc-Thr(Ac₃AcNH-α-Gal)-OH

Chemical Properties

Molecular Weight	670.66
Formula	C33H38N2O13
Cas No.	116783-35-8

Storage & Solubility Information

Storage	keep away from moisture Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	H2O: soluble

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Keywords

Fmoc-Thr(Ac₃AcNH-a-Gal)-OHZINC 77292789Fmoc-Thr(Ac₃AcNH-alpha-Gal)-OHinhibitInhibitorZINC-77292789ZINC77292789Fmoc-Thr[GalNAc(Ac)3-a-D]-OHFmoc-Thr[GalNAc(Ac)3-alpha-D]-OH